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Review

Mitochondrial cytopathy in adults: What we know so far

Bruce H. Cohen, MD and Deborah R. Gold, MD
Cleveland Clinic Journal of Medicine July 2001, 68 (7) 625-642;
Bruce H. Cohen
Chief, Section of Pediatric Neurology, Departments of Neurology, Neurosurgery, and the Taussig Cancer Center, Cleveland Clinic
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Deborah R. Gold
Section of Pediatric Neurology, Department of Neurology, Cleveland Clinic
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ABSTRACT

Mitochondrial cytopathies are a diverse group of inherited and acquired disorders that result in inadequate energy production. They can be caused by inheritable genetic mutations, acquired somatic mutations, exposure to toxins (including some prescription medications), and the aging process itself. In addition, a number of well-described diseases can decrease mitochondrial energy production; these include hyperthyroidism, hypothyroidism, and hyperlipidemia.

  • Copyright © 2001 The Cleveland Clinic Foundation. All Rights Reserved.
  1. Bruce H. Cohen, MD⇑ and
  2. Deborah R. Gold, MD
  1. Chief, Section of Pediatric Neurology, Departments of Neurology, Neurosurgery, and the Taussig Cancer Center, Cleveland Clinic
  2. Section of Pediatric Neurology, Department of Neurology, Cleveland Clinic
  1. ADDRESS:
    Bruce H. Cohen, MD, Chief, Section of Pediatric Neurology, S80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.

ABSTRACT

Mitochondrial cytopathies are a diverse group of inherited and acquired disorders that result in inadequate energy production. They can be caused by inheritable genetic mutations, acquired somatic mutations, exposure to toxins (including some prescription medications), and the aging process itself. In addition, a number of well-described diseases can decrease mitochondrial energy production; these include hyperthyroidism, hypothyroidism, and hyperlipidemia.

  • Copyright © 2001 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 68 (7)
Cleveland Clinic Journal of Medicine
Vol. 68, Issue 7
1 Jul 2001
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Mitochondrial cytopathy in adults: What we know so far
Bruce H. Cohen, Deborah R. Gold
Cleveland Clinic Journal of Medicine Jul 2001, 68 (7) 625-642;

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Mitochondrial cytopathy in adults: What we know so far
Bruce H. Cohen, Deborah R. Gold
Cleveland Clinic Journal of Medicine Jul 2001, 68 (7) 625-642;
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