ABSTRACT
Monoamine oxidase (MAO) inhibitors were the first antidepressants introduced, but their use has dwindled because of their reported side effects, their food and drug interactions, and the introduction of other classes of agents. However, interest in MAO inhibitors is reviving. Here, we discuss their use, risks, and benefits in clinical medicine.
Footnotes
↵* Dr. Malone has disclosed that he is on the speakers’ bureaus of Eli Lilly and BMS and receives research funding from Medtronic.
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