RT Journal Article
SR Electronic
T1 Dronedarone for atrial fibrillation: How does it compare with amiodarone?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 179
OP 185
DO 10.3949/ccjm.78a.10049
VO 78
IS 3
A1 Neelima Penugonda
A1 Adam Mohmand-Borkowski
A1 James F. Burke
YR 2011
UL http://www.ccjm.org/content/78/3/179.abstract
AB Dronedarone (Multaq), an analogue of amiodarone (Cordarone), was designed to cause fewer adverse effects than the parent compound. Studies have indeed shown dronedarone to be safer than amiodarone, but less effective. Its official indication is to reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation or atrial flutter and other cardiovascular risk factors, reflecting the parameters of its effectiveness in clinical trials.