PT - JOURNAL ARTICLE AU - Esteban Walker AU - Adrian V. Hernandez AU - Michael W. Kattan TI - Meta-analysis: Its strengths and limitations DP - 2008 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 431--439 VI - 75 IP - 6 4099 - http://www.ccjm.org/content/75/6/431.short 4100 - http://www.ccjm.org/content/75/6/431.full SO - Cleve Clin J Med2008 Jun 01; 75 AB - Nowadays, doctors face an overwhelming amount of information, even in narrow areas of interest. In response, reviews designed to summarize the large volumes of information are frequently published. When a review is done systematically, following certain criteria, and the results are pooled and analyzed quantitatively, it is called a meta-analysis. A well-designed meta-analysis can provide valuable information for researchers, policymakers, and clinicians. However, there are many critical caveats in performing and interpreting them, and thus many ways in which meta-analyses can yield misleading information.