Objective: To evaluate pre-and postoperative clinical parameters associated with improvement
of diabetes up to 4 years after laparoscopic Roux-en-Y gastric bypass (LRYGBP) in …

Both bone mass and serum leptin levels are increased in obesity. Because osteoblasts and
adipocytes arise from a common precursor in bone marrow, we assessed the effects of …

Bone mineral density increases with fat body mass, and obesity has a protective effect against
osteoporosis. However, the relationship between fat body mass and bone mineral density …

Leptin is a circulating hormone secreted mainly by adipose tissue. Recent studies have shown
leptin production by other tissues, including the placenta, stomach, and mammary tissues…

During the last 2 decades, the evolution of sensitive diagnostic techniques has significantly
improved and simplified endocrine practice. Technologic advances have expanded …

Objective: Evaluating the short-term safety and tolerability of a VLCK diet (< 50 g of
carbohydrate daily) in an interventional weight loss program including lifestyle and behavioral …

Leptin is a circulating hormone secreted by adipose and a few other tissues. The leptin
receptor consists of a single transmembrane-spanning polypeptide that is present as a long …

Objective: To construct and validate a scoring system for evidence-based selection of
bariatric and metabolic surgery procedures according to severity of type 2 diabetes (T2DM). …

Leptin exerts important effects on the regulation of food intake and energy expenditure by
acting in the brain. Leptin is secreted by adipocytes into the bloodstream and must gain access …

Leptin (OB protein), the product of the adipose-specific ob gene, exerts important effects in the
regulation of food intake and energy expenditure. Based upon results from animal studies, …