Back to the basics on pressure and fat
Sometimes we may be too smart about the nuances of clinical science and get distracted from our goal of improving patient outcomes.
B.F. MANDELL

The two faces of the 'good' cholesterol
Ordinarily anti-inflammatory and protective, HDL sometimes becomes proinflammatory. Thus, the functional properties—not simply the level— may need to be considered and optimized.
B.J. ANSELL

Exposing the complexity of HDL
HDL is a heterogeneous population of particles, and we should not be surprised if these particles differ in their effect on the arterial wall.
S.J. NICHOLLS

Update on adolescent immunization: Pertussis, meningococcus, HPV, and the future
Preteens and teenagers will be getting more shots. The extra visits will give us another opportunity to talk to these young people about high-risk behavior.
S.H. YEH and J.M. LIEBERMAN

Short-term prognosis after a TIA: A simple score predicts risk
This article discusses the defining features of transient ischemic attacks (TIAs), and their immediate evaluation and management.
S.C. JOHNSTON

Diagnostic strategies for suspected pulmonary arterial hypertension: A primer for the internist
If not recognized early, pulmonary arterial hypertension can have devastating consequences. Recent advances have led to improved diagnostic strategies.
O.A. MINAI and M.M. BUDEV

What is adequate hypertension control? Having your dinner and dessert too
Controlling the blood pressure per se should be our primary concern ("dinner"), while choosing agents that may have added benefit in specific situations is secondary ("dessert").
J.W. GRAVES

The Women's Health Initiative and hormone therapy, 5 years later
"Although I knew then that we were in for a big change, I did not anticipate the total impact."
S.R. JOHNSON

Vulnerable patients are between a 'ROC and a hard place': Yes, it's time to screen for coronary artery disease
In the September 2007 issue, Dr. Michael Lauer rejected the recently proposed Screening for Heart Attack prevention and Education (SHAPE) guidelines. The authors of the SHAPE guidelines would like to address his arguments.
M. NAGHAVI and H.S. HECHT