Coxibs: Evolution of a
Revolutionary Class

      

 

Evolving Concepts and Issues
Surrounding Cox-2 Inhibitors

 

Special Edition
2002

Supplement 1 to Volume 69

This publication is supported
by an independent 
educational grant from 
Merck & Co.

Editorial development by
 New World Health

 

 

 

 

 

 

 

 

 

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TABLE OF CONTENTS
Preface

Foreword
M.C. HOCHBERG, MD, MPH, SUPPLEMENT EDITOR

Development and clinical application of COX-2-selective inhibitors for the treatment of osteoarthritis and rheumatoid arthritis
C.O. BINGHAM III, MD
Cyclooxygenase-2-selective inhibitors: Translating pharmacology into clinical utility
B.N. CRONSTEIN, MD
COX-2-selective inhibitors in the treatment of arthritis
T.J. SCHNITZER, MD, PhD, 
AND M.C. HOCHBERG, MD, MPH
Gastrointestinal safety and tolerability of nonselective nonsteroidal anti-inflammatory agents and cyclooxygenase-2-selective inhibitors
D.A. PEURA, MD

Outcomes studies of the gastrointestinal safety of cyclooxygenase-2 inhibitors
J.M. SCHEIMAN, MD

Current perspective on the cardiovascular effects of coxibs
M.A. KONSTAM, MD,
AND M.R. WEIR, MD

Renal effects of nonselective NSAIDS and coxibs
M.R. WEIR, MD

Developing an economic rationale for the use of selective COX-2 inhibitors for patients at risk for NSAID gastropathy
A.M. FENDRICK, MD

Cyclooxygenase-2-selective inhibitors in the management of acute and perioperative pain
W.A. KATZ, MD

Emerging options with coxib therapy
M.J. LEMA, MD, PhD

 

Copyright© 2002 by the Cleveland Clinic Educational Foundation.

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