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Cleveland Clinic Journal of Medicine

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Current Issue

01 Dec 2025 (Vol. 92 Issue 12) Table of Contents
Cleveland Clinic Journal of Medicine: 92 (12)

Issue highlights

  • Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both
  • LADA: A case for starting insulin therapy at diagnosis
  • Should I consider low-dose rivaroxaban (2.5 mg) for my patient with peripheral artery disease?
  • Skin manifestations of mpox

Summaries from Kidney Week 2025

Summaries from ACR Convergence 2025

Featured Articles

  • How can I select the right thyroid hormone formulation for my patient with hypothyroidism?
    December 01, 2025
  • Trident sign in osmotic demyelination syndrome
    December 01, 2025
  • Diabetes: Putting off until tomorrow what could happen today can be good
    December 01, 2025
  • Multiple scabietic nodules on the scrotum in a patient living with HIV infection
    November 03, 2025
  • Teprotumumab for thyroid eye disease: A reality check
    November 03, 2025
  • Lipoprotein(a) in clinical practice: What clinicians need to know
    November 03, 2025
  • Nearly a century of using glucocorticoids in patients with active infection
    October 01, 2025
  • MDA5 dermatomyositis: Unveiling a potentially life-threatening disease
    October 01, 2025
  • What is the role of cystatin C in estimating glomerular filtration rate and guiding medication...
    September 02, 2025
  • An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel
    September 02, 2025
  • Acute respiratory distress syndrome: Why a definition matters
    September 02, 2025
  • Does my patient need testing for PFAS ‘forever chemicals’?
    August 01, 2025
  • Newer diabetes drugs: Surprising shared benefits and unique side effects
    August 01, 2025
  • The overlooked and undertreated perils of premature ovarian insufficiency
    August 01, 2025
  • Insights from the LAAOS III trial of left atrial appendage occlusion to prevent stroke in atrial...
    July 01, 2025
  • Breast cancer risk and screening for transgender and gender-diverse individuals
    July 01, 2025
  • Immunotherapy meets William Shakespeare
    July 01, 2025

Latest Articles

  • You have access
    Barriers to cancer screening in transgender women
    Maryam Sattari, MD, MS
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 721; DOI: https://doi.org/10.3949/ccjm.92c.12001
  • You have access
    Corticosteroids in severe community-acquired pneumonia
    Enmanuel A. Leiva-Murillo, MD and Rosanel Amaro-Rodríguez, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 723-724; DOI: https://doi.org/10.3949/ccjm.92c.12005
  • You have access
    Should I consider low-dose rivaroxaban (2.5 mg) for my patient with peripheral artery disease?
    Pranay Marlecha, MD, Deborah Hornacek, MD and Pulkit Chaudhury, MD, MS
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 742-744; DOI: https://doi.org/10.3949/ccjm.92a.25065

    For patients with high ischemic risk, rivaroxaban 2.5 mg twice daily with aspirin 81 or 100 mg daily is a proven strategy to reduce major cardiovascular and limb events.

  • You have access
    How should I incorporate emergency contraception counseling into my practice?
    Alexa R. Wilden, MD and Heather M. Wainstein, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 738-741; DOI: https://doi.org/10.3949/ccjm.92a.25029

    Emergency contraception counseling should be provided routinely to women at risk of unintended pregnancy as part of counseling on reproductive goals.

  • You have access
    Trident sign in osmotic demyelination syndrome
    Erin Equinozzi, MSc, Clement D. Lee, MD, MSc and Pamela Schaefer, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 732-733; DOI: https://doi.org/10.3949/ccjm.92a.24080

    Brain magnetic resonance imaging showed a confluent trident-shaped lesion in the central pons 1 week after correction of the patient’s chronic hyponatremia.

  • You have access
    Cystatin C for estimating glomerular filtration rate and guiding medication dosing
    Shahzeb Saeed, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722-723; DOI: https://doi.org/10.3949/ccjm.92c.12004
  • You have access
    Diabetes: Putting off until tomorrow what could happen today can be good
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 715-717; DOI: https://doi.org/10.3949/ccjm.92b.12025

    Prevention of beta-cell loss and preservation of endogenous insulin production have been attractive treatment prerogatives in type 1 diabetes.

  • You have access
    All menopausal hormone therapy is not alike
    Henry H. Lindner, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 721-722; DOI: https://doi.org/10.3949/ccjm.92c.12002
  • You have access
    Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both
    CME article
    Michelle D. Lundholm, MD and Keren Zhou, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 757-763; DOI: https://doi.org/10.3949/ccjm.92a.25069

    Latent autoimmune diabetes in adults shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy.

  • You have access
    In reply: All menopausal hormone therapy is not alike
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722; DOI: https://doi.org/10.3949/ccjm.92c.12003
View more latest articles
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Finding the cause of severe hypokalemia: A 4-step approach
How should I incorporate emergency contraception counseling into my practice?
Acute transient phlebitis after a morphine infusion
Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
Failure to thrive in hospitalized older adults: More than a ‘social admission’
What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
No surprise, all inflammation is not created equal as it relates to cardiovascular disease
Benign migratory glossitis
Flexibility is warranted in applying prescribing guidelines
How can I help my pregnant patients quit using tobacco?
Half-moccasin distribution of acute tinea pedis
Cerebrovascular complications in infective endocarditis: Challenges and considerations in management
Evolving paradigms in hypertension management: Fixed-dose single-pill combinations and future therapies
Refractory granuloma annulare

Cleveland Clinic Journal of Medicine, published by Cleveland Clinic, provides busy clinicians with practical information to promote better patient care.

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