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Editorial

Blood pressure management in the wake of SPRINT

Edward J. Filippone, MD, FACP and Andrew J. Foy, MD
Cleveland Clinic Journal of Medicine March 2016, 83 (3) 196-198; DOI: https://doi.org/10.3949/ccjm.83a.16015
Edward J. Filippone
Clinical Associate Professor of Medicine, Sydney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA
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Andrew J. Foy
Assistant Professor of Medicine and Public Health Sciences, Penn State Milton S. Hershey Medical Center, Hershey, PA
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  • For correspondence: afoy@hmc.psu.edu
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REFERENCES

  1. ↵
    1. Lim SS,
    2. Vos T,
    3. Flaxman AD,
    4. et al
    . A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380:2224–2260.
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    1. Prospective Studies Collaboration
    . Age-specific relevance of usual blood pressure to vascular mortality: a metaanalysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360:1903–1913.
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    1. Psaty BM,
    2. Smith NL,
    3. Siscovick DS,
    4. et al
    . Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis. JAMA 1997; 277:739–745.
    OpenUrlCrossRefPubMed
  4. ↵
    1. SPRINT Research Group
    2. Wright JT Jr.,
    3. Williamson JD,
    4. Whelton PK,
    5. et al
    . A randomized trial of intensive versus standard blood-pressure control. N Engl J Med 2015; 373:2103–2116.
    OpenUrlCrossRefPubMed
  5. ↵
    1. ACCORD Study Group
    2. Cushman WC,
    3. Evans GW,
    4. Byington RP,
    5. et al
    . Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med 2010; 362:1575–1585.
    OpenUrlCrossRefPubMed
  6. ↵
    1. SPS3 Study Group
    2. Benavente OR,
    3. Coffey CS,
    4. Conwit R,
    5. et al
    . Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial. Lancet 2013; 382:507–515.
    OpenUrlCrossRefPubMed
  7. ↵
    1. Filippone EJ,
    2. Foy A,
    3. Newman E
    . Goal-directed antihypertensive therapy: lower may not always be better. Cleve Clin J Med 2011; 78:123–133.
    OpenUrlAbstract/FREE Full Text
  8. ↵
    1. Lv J,
    2. Neal B,
    3. Ehteshami P,
    4. et al
    . Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis. PLoS Med 2012; 9:e1001293.
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  9. ↵
    1. Thomas G,
    2. Nally JV,
    3. Pohl MA
    . Interpreting SPRINT: how low should you go? Cleve Clin J Med 2016; 83:187–195.
    OpenUrlAbstract/FREE Full Text

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Cleveland Clinic Journal of Medicine: 83 (3)
Cleveland Clinic Journal of Medicine
Vol. 83, Issue 3
1 Mar 2016
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Blood pressure management in the wake of SPRINT
Edward J. Filippone, Andrew J. Foy
Cleveland Clinic Journal of Medicine Mar 2016, 83 (3) 196-198; DOI: 10.3949/ccjm.83a.16015

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Blood pressure management in the wake of SPRINT
Edward J. Filippone, Andrew J. Foy
Cleveland Clinic Journal of Medicine Mar 2016, 83 (3) 196-198; DOI: 10.3949/ccjm.83a.16015
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