ABSTRACT
Thrombotic thrombocytopenic purpura, Shiga toxin hemolytic uremic syndrome, atypical hemolytic uremic syndrome, and antiphospholipid syndrome are thrombotic microangiopathies that present similarly but arise from different causes. Management depends on distinguishing them promptly and providing targeted therapy.
Footnotes
Medical Grand Rounds articles are based on edited transcripts from Medicine Grand Rounds presentations at Cleveland Clinic. They are approved by the author but are not peer-reviewed.
Dr. Appel has received research grants or consultantships from or is on the speakers’ bureaus of the following organizations: Abbott Laboratories, Alexion, Astra Zeneca, BMS, Bristol-Myers Squibb, EMD Serono, Genentech, Genzyme, Questcor, Regulus, Sanofi Aventis, Takeda, UpToDate.
- Copyright © 2017 The Cleveland Clinic Foundation. All Rights Reserved.
- Gerald B. Appel, MD⇑
- Director of The Glomerular Center, New York-Presbyterian Hospital, and Professor of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
- ADDRESS:
Gerald B. Appel, MD, Columbia University Medical Center, 622 West 168th Street, Room 4124, New York, NY 10032; gba2{at}columbia.edu
ABSTRACT
Thrombotic thrombocytopenic purpura, Shiga toxin hemolytic uremic syndrome, atypical hemolytic uremic syndrome, and antiphospholipid syndrome are thrombotic microangiopathies that present similarly but arise from different causes. Management depends on distinguishing them promptly and providing targeted therapy.
Footnotes
Medical Grand Rounds articles are based on edited transcripts from Medicine Grand Rounds presentations at Cleveland Clinic. They are approved by the author but are not peer-reviewed.
Dr. Appel has received research grants or consultantships from or is on the speakers’ bureaus of the following organizations: Abbott Laboratories, Alexion, Astra Zeneca, BMS, Bristol-Myers Squibb, EMD Serono, Genentech, Genzyme, Questcor, Regulus, Sanofi Aventis, Takeda, UpToDate.
- Copyright © 2017 The Cleveland Clinic Foundation. All Rights Reserved.