Table of Contents

Lipoprotein(a) was once believed to play no contributory role in the development of cardiovascular disease. That storyline has since flipped.

A 21-year-old man presented with pruritic erythematous papules and nodules on the scrotum and linear keratotic burrows on the right wrist.

Failure to thrive documented as an admitting diagnosis presents an opportunity to identify, articulate, and begin to ameliorate the true underlying causes of the patient’s health deficits.

Therapy should be continued even if left ventricular ejection fraction improves, as normalization or improvement does not guarantee a permanent recovery.

The authors discuss 3 unresolved questions about de-escalating and escalating guideline-directed medical therapy in patients with improved ejection fraction.

Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.

Elevated lipoprotein(a) by itself is not an indication for statin therapy, but its presence supports earlier or more aggressive preventive therapy.

The goals of treating obesity in older adults are to ease its complications and improve functional status and quality of life, with or without weight loss.

A better understanding of the pathophysiology of this autoimmune disorder has led to innovative insights into its treatment, but long-term management remains a challenge.

Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.