Table of Contents

December 01, 2025; Volume 92, Issue 12

  • From the Editor

  • The Clinical Picture

      • Trident sign in osmotic demyelination syndrome

        Erin Equinozzi, MSc, Clement D. Lee, MD, MSc and Pamela Schaefer, MD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 732-733;
        • DOI: https://doi.org/10.3949/ccjm.92a.24080

        • Brain magnetic resonance imaging showed a confluent trident-shaped lesion in the central pons 1 week after correction of the patient’s chronic hyponatremia.

      • Acute transient phlebitis after a morphine infusion

        Alexandros Makris, MD, PhD, MSc, Alexandros Nikas, MD and Anastasios Bontozis, MD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 734-735;
        • DOI: https://doi.org/10.3949/ccjm.92a.25007

        • Prominent ascending erythema outlining the infused vein and its proximal branches developed quickly after infusion.

      • Skin manifestations of mpox

        James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737;
        • DOI: https://doi.org/10.3949/ccjm.92a.25022

        • The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

  • 1-Minute Consult

      • How should I incorporate emergency contraception counseling into my practice?

        Alexa R. Wilden, MD and Heather M. Wainstein, MD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 738-741;
        • DOI: https://doi.org/10.3949/ccjm.92a.25029

        • Emergency contraception counseling should be provided routinely to women at risk of unintended pregnancy as part of counseling on reproductive goals.

      • Should I consider low-dose rivaroxaban (2.5 mg) for my patient with peripheral artery disease?

        Pranay Marlecha, MD, Deborah Hornacek, MD and Pulkit Chaudhury, MD, MS
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 742-744;
        • DOI: https://doi.org/10.3949/ccjm.92a.25065

        • For patients with high ischemic risk, rivaroxaban 2.5 mg twice daily with aspirin 81 or 100 mg daily is a proven strategy to reduce major cardiovascular and limb events.

      • How can I select the right thyroid hormone formulation for my patient with hypothyroidism?

        Lea El Hage, MD and Vinni Makin, MBBS, MD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 745-747;
        • DOI: https://doi.org/10.3949/ccjm.92a.25042

        • Knowing the features of the available thyroid hormone formulations can provide a starting point for individualizing therapy for patients who have concerns about product formulations or remain symptomatic despite a normal thyroid-stimulating hormone level.

  • Symptoms to Diagnosis

      • TOC Icon

        Finding the cause of severe hypokalemia: A 4-step approach

        Enmanuel A. Leiva-Murillo, MD, Erwin Bechtold-Javier, MD, Pol Candela-Parrilla, MD and Ana Matas-García, MD, PhD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 748-756;
        • DOI: https://doi.org/10.3949/ccjm.92a.25055

        • This case illustrates the approach to a group of conditions associated with hypokalemia that usually pose a diagnostic challenge.

  • Review

  • Editorial

      • LADA: A case for starting insulin therapy at diagnosis

        Byron J. Hoogwerf, MD
        • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 764-766;
        • DOI: https://doi.org/10.3949/ccjm.92a.25084

        • The author discusses factors that support starting insulin therapy at diagnosis in all patients with latent autoimmune diabetes in adults.

  • Letter to the Editor

PreviousNext
Back to top

In this issue

Cleveland Clinic Journal of Medicine

Cleveland Clinic Journal of Medicine

Vol. 92, Issue 12

1 Dec 2025

Table of Contents Table of Contents (PDF) Index by author Complete Issue (PDF)

Issue highlights

Sign up for alerts

Jump to

More...
More...