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1-Minute Consult

What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?

Karthik Meiyappan Udayappan, MD and Christopher V. Anstine, MD
Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276; DOI: https://doi.org/10.3949/ccjm.92a.24052
Karthik Meiyappan Udayappan
Senior Associate Consultant, Department of Medicine, Division of General Internal Medicine, Mayo Clinic, Rochester, MN; Instructor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN
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  • For correspondence: [email protected]
Christopher V. Anstine
Consultant, Department of Medicine, Division of General Internal Medicine, Mayo Clinic, Rochester, MN; Assistant Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN
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    Figure 1

    Views of the patient’s fingers and fingernails. (A) Superior view of early clubbing. (B) Profile view of early clubbing. (C) The depth at the nail fold is greater than the depth at the distal interphalangeal joint (DIP), which confirms the presence of clubbing. Point D (the hyponychium) is lower than the extension of line AB created from the DIP joint to the nail fold. This angle ABD (hyponychial angle) is greater than 180 degrees, also confirming clubbing. The profile angle (or the Lovibond angle) is visually the hardest to estimate. This angle, formed by ABC, is also greater than 180 degrees, which would prevent a diamond-shaped window from appearing when this digit is opposed nail-to-nail with the corresponding digit on the opposite hand with angle ABC greater than 180 degrees (Schamroth sign).

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    Figure 2

    Suggested approach to evaluation of bilateral clubbing.

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Cleveland Clinic Journal of Medicine: 92 (5)
Cleveland Clinic Journal of Medicine
Vol. 92, Issue 5
1 May 2025
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What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
Karthik Meiyappan Udayappan, Christopher V. Anstine
Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276; DOI: 10.3949/ccjm.92a.24052

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What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
Karthik Meiyappan Udayappan, Christopher V. Anstine
Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276; DOI: 10.3949/ccjm.92a.24052
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  • Article
    • DETECTING CLUBBING ON EXAMINATION
    • THE RELATIONSHIP OF CLUBBING TO HYPERTROPHIC OSTEOARTHROPATHY
    • DISEASES ASSOCIATED WITH CLUBBING
    • SEARCHING FOR THE CAUSE OF CLUBBING
    • THE BOTTOM LINE
    • DISCLOSURES
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