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1-Minute Consult

How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?

Rupayan Kundu, MD, Arjun Chatterjee, MD, Jessica Philpott, MD, PhD and Lucy Boyce Kennedy, MD
Cleveland Clinic Journal of Medicine July 2025, 92 (7) 401-405; DOI: https://doi.org/10.3949/ccjm.92a.24090
Rupayan Kundu
Department of Internal Medicine, Cleveland Clinic, Cleveland, OH
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Arjun Chatterjee
Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH
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Jessica Philpott
Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Lucy Boyce Kennedy
Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
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Article Information

vol. 92 no. 7 401-405
DOI 
https://doi.org/10.3949/ccjm.92a.24090
PubMed 
40592539

Published By 
Cleveland Clinic Journal of Medicine
Print ISSN 
0891-1150
Online ISSN 
1939-2869
History 
  • Published online July 1, 2025.

Copyright & Usage 
Copyright © 2025 The Cleveland Clinic Foundation. All Rights Reserved.

Author Information

  1. Rupayan Kundu, MD
  1. Department of Internal Medicine, Cleveland Clinic, Cleveland, OH
  1. Arjun Chatterjee, MD
  1. Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH
  1. Jessica Philpott, MD, PhD
  1. Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Lucy Boyce Kennedy, MD⇑
  1. Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
  1. Address:
    Lucy Boyce Kennedy, MD, Department of Hematology and Medical Oncology, CA-60, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, kennedl5{at}ccf.org
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Cleveland Clinic Journal of Medicine: 92 (7)
Cleveland Clinic Journal of Medicine
Vol. 92, Issue 7
1 Jul 2025
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How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?
Rupayan Kundu, Arjun Chatterjee, Jessica Philpott, Lucy Boyce Kennedy
Cleveland Clinic Journal of Medicine Jul 2025, 92 (7) 401-405; DOI: 10.3949/ccjm.92a.24090

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How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?
Rupayan Kundu, Arjun Chatterjee, Jessica Philpott, Lucy Boyce Kennedy
Cleveland Clinic Journal of Medicine Jul 2025, 92 (7) 401-405; DOI: 10.3949/ccjm.92a.24090
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  • Article
    • WHEN TO SUSPECT COLITIS IS RELATED TO IMMUNOTHERAPY
    • ASSESSING THE SEVERITY OF DIARRHEA AND COLITIS
    • WHAT IS THE WORKUP FOR SUSPECTED DIARRHEA AND COLITIS FROM IMMUNOTHERAPY?
    • HOW SHOULD WE MANAGE DIARRHEA OR COLITIS?
    • WHEN DO WE RESTART THERAPY?
    • HOW SHOULD WE MANAGE RECURRENCE OF IMMUNE-MEDIATED COLITIS?
    • THE BOTTOM LINE
    • DISCLOSURES
    • REFERENCES
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