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Cleveland Clinic Journal of Medicine

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Table of Contents

September 01, 2025; Volume 92,Issue 9

From the Editor

  • You have access
    Flexibility is warranted in applying prescribing guidelines
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 520-521; DOI: https://doi.org/10.3949/ccjm.92b.09025

    Discontinuation of benzodiazepines in chronic users may be associated with a small increase in mortality and a higher risk of adverse events, especially in the short term after cessation.

The Clinical Picture

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    Half-moccasin distribution of acute tinea pedis
    Yusuke Ito, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 529-530; DOI: https://doi.org/10.3949/ccjm.92a.24085

    An 84-year-old woman presented with a week-long history of pruritus on the sole of her right foot.

Commentary

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    Benzodiazepines: Caught between patient needs and guidelines
    Jasleen Kaur, MD, Vania Modesto-Lowe, MD, MPH and Margaret M. Chaplin, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 531-535; DOI: https://doi.org/10.3949/ccjm.92a.25019

    Negative sentiment about benzodiazepines has intensified in recent years, and there is increasing emphasis on deprescribing even for people who have had no ill effects from them.

1-Minute Consult

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    How can I help my pregnant patients quit using tobacco?
    Moronkeji Fagbemi, MD, Ivie Odiase, MD and Anna Fagbemi, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 542-545; DOI: https://doi.org/10.3949/ccjm.92a.25008

    Clinicians should screen for tobacco use and follow-up with pregnancy-specific messaging during each visit, building on any motivation the patient has to quit.

  • You have access
    What is the role of cystatin C in estimating glomerular filtration rate and guiding medication dosing?
    Joseph Hajj, MD, Allaa Almoushref, MD, Georges Nakhoul, MD and George Thomas, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 546-549; DOI: https://doi.org/10.3949/ccjm.92a.25036

    A dual-marker strategy using both serum creatinine and cystatin C is recommended for certain patients in whom serum creatinine alone may not accurately reflect kidney function.

Commentary

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    Collaborative musculoskeletal care: The role for chiropractors
    Samuel M. Schut, DC, Logan J. Benjamin, DC, MPH and Timothy J. Williamson, DC, MS
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 550-554; DOI: https://doi.org/10.3949/ccjm.92a.25014

    Integrating chiropractors into multidisciplinary care settings can help support guideline-concordant care and may free up internists to see more patients with other problems.

Review

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    Optimizing hypertension treatment: Evidence-based approaches and new drugs
    CME article
    Astefanos Al-Dalakta, MD, Ahmad Ghanem, MD, Chadi Tabaja, MD, Issam Motairek, MD, Abdel Hadi El Hajjar, MD and Luke J. Laffin, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 555-564; DOI: https://doi.org/10.3949/ccjm.92a.24119

    The authors discuss current evidence-based approaches to managing hypertension and optimizing blood pressure control through a series of cases representing common clinical scenarios.

  • Acute respiratory distress syndrome: Why a definition matters
    You have access
    Acute respiratory distress syndrome: Why a definition matters
    Christine Girard, MD, Divyajot Sadana, MD, Shewit Giovanni, MD, MS, Heather Torbic, PharmD, BCPS, BCCCP and Abhijit Duggal, MD, MPH, MSc
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 565-571; DOI: https://doi.org/10.3949/ccjm.92a.24115

    The new definition brings acute respiratory distress syndrome into the realm of physicians working on hospital general medicine wards.

  • You have access
    An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel
    Rujuta Takalkar, BS, Andrea Lorenzo, MD, MS and Suneela Vegunta, MD, NCMP
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 572-576; DOI: https://doi.org/10.3949/ccjm.92a.24108

    Oral norgestrel, the first daily oral contraceptive pill available over the counter in the United States, is a safe, effective addition to existing over-the-counter contraceptive options.

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In this issue

Cleveland Clinic Journal of Medicine: 92 (9)
Cleveland Clinic Journal of Medicine
Vol. 92, Issue 9
1 Sep 2025
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Complete Issue (PDF)

Issue highlights

  • Optimizing hypertension treatment: Evidence-based approaches and new drugs
  • Benzodiazepines: Caught between patient needs and guidelines
  • What is the role of cystatin C in estimating glomerular filtration rate and guiding medication dosing?
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A new direction in pain management?
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Finding the cause of severe hypokalemia: A 4-step approach
How should I incorporate emergency contraception counseling into my practice?
Acute transient phlebitis after a morphine infusion
Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
Failure to thrive in hospitalized older adults: More than a ‘social admission’
What is the optimal time for bone density screening in patients with premature ovarian insufficiency?

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