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Cleveland Clinic Journal of Medicine

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Table of Contents

January 01, 2026; Volume 93,Issue 1

From the Editor

  • You have access
    More on the myths and perceived magic of corticosteroids
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 6-7; DOI: https://doi.org/10.3949/ccjm.93b.01026

    It is widely accepted that corticosteroids can partially prevent infusion reactions to intravenous diagnostic and therapeutic agents, but evidence to support this concept is scant.

The Clinical Picture

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    Multicentric reticulohistiocytosis
    Atul Khasnis, MD, MS and Joseph M. Dyer, DO
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 9-11; DOI: https://doi.org/10.3949/ccjm.93a.24124

    A 58-year-old man presented with a 2-month history of joint pain and swelling and a rash.

  • You have access
    Pseudoxanthoma elasticum
    Kathleen Kramer, MD, Sama Alazawi, DO and Rudy Schmiedecke, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 13-14; DOI: https://doi.org/10.3949/ccjm.93a.25021

    The patient presented for evaluation of yellowish plaques on her neck that had been present since childhood.

1-Minute Consult

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    Atrial fibrillation in patients with obesity: How can we optimize management?
    Asim Kichloo, MD, Ivan Magallanes Marrufo, MPH and Suhaib Andrabi, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 17-20; DOI: https://doi.org/10.3949/ccjm.93a.25032

    Heart rate and rhythm control therapies often must be adjusted when treating patients with obesity, while other measures can reduce the onset or recurrence of atrial fibrillation.

Commentary

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    Vaccine hesitancy: Where are we heading?
    Sherif Beniameen Mossad, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 21-26; DOI: https://doi.org/10.3949/ccjm.93a.25104

    Vaccination recently was hailed as one of the top 10 public health achievements of the 20th century; now, the World Health Organization lists vaccine hesitancy among the top 10 threats to global health.

Symptoms to Diagnosis

  • A young woman with Kallmann syndrome and acute neurologic symptoms
    You have access
    A young woman with Kallmann syndrome and acute neurologic symptoms
    Jumaina F. Ali, MBChB, Adhithya Sankar, MBChB, PhD, Mohammed S. O. Ahmed, MBBS, MSc, Mark Woodward, BSc (Hons), MBChB and Akheel A. Syed, MBBS, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 29-34; DOI: https://doi.org/10.3949/ccjm.93a.25010

    Diagnoses considered on initial presentation included conditions that present with stroke-like symptoms such as seizure, hemiplegic migraine, transient ischemic attack, and brain tumor.

Current Drug Therapy

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    Update on antiobesity pharmacotherapy in adults: Current and emerging options
    Farah Ziyadeh, MD, Sara Saliba, MD, RD, Dania Salih Bacha, MD, Yael Mauer, MD, MPH, Marcio L. Griebeler, MD, DABOM and Bartolome Burguera, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 36-46; DOI: https://doi.org/10.3949/ccjm.93a.24112

    The authors review antiobesity medications that are currently available or under investigation and discuss how to personalize obesity treatment.

Review

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    Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?
    CME article
    Dylan T. Timberlake, MD, Sushmitha Boppana, MD and James Fernandez, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 47-53; DOI: https://doi.org/10.3949/ccjm.93a.25026

    The data and recommendations about corticosteroid pretreatment vary by medication class and the individual medication, necessitating a medication- and patient-specific approach.

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In this issue

Cleveland Clinic Journal of Medicine: 93 (1)
Cleveland Clinic Journal of Medicine
Vol. 93, Issue 1
1 Jan 2026
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Complete Issue (PDF)

Issue highlights

  • Update on antiobesity pharmacotherapy in adults: Current and emerging options
  • Vaccine hesitancy: Where are we heading?
  • Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?
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A young woman with Kallmann syndrome and acute neurologic symptoms
Multicentric reticulohistiocytosis
Finding the cause of severe hypokalemia: A 4-step approach
How should I incorporate emergency contraception counseling into my practice?
Acute transient phlebitis after a morphine infusion
Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
Failure to thrive in hospitalized older adults: More than a ‘social admission’
What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
No surprise, all inflammation is not created equal as it relates to cardiovascular disease
Benign migratory glossitis
Flexibility is warranted in applying prescribing guidelines
How can I help my pregnant patients quit using tobacco?
Half-moccasin distribution of acute tinea pedis
Cerebrovascular complications in infective endocarditis: Challenges and considerations in management
Evolving paradigms in hypertension management: Fixed-dose single-pill combinations and future therapies
Refractory granuloma annulare

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