Latest Articles

  • In reply: All menopausal hormone therapy is not alike
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722; DOI: https://doi.org/10.3949/ccjm.92c.12003
  • Skin manifestations of mpox
    James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737; DOI: https://doi.org/10.3949/ccjm.92a.25022

    The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

  • In Reply: Corticosteroids in severe community-acquired pneumonia
    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, Cody O’Rear, DO and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 724; DOI: https://doi.org/10.3949/ccjm.92c.12006
  • How can I select the right thyroid hormone formulation for my patient with hypothyroidism?
    Lea El Hage, MD and Vinni Makin, MBBS, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 745-747; DOI: https://doi.org/10.3949/ccjm.92a.25042

    Knowing the features of the available thyroid hormone formulations can provide a starting point for individualizing therapy for patients who have concerns about product formulations or remain symptomatic despite a normal thyroid-stimulating hormone level.

  • LADA: A case for starting insulin therapy at diagnosis
    Byron J. Hoogwerf, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 764-766; DOI: https://doi.org/10.3949/ccjm.92a.25084

    The author discusses factors that support starting insulin therapy at diagnosis in all patients with latent autoimmune diabetes in adults.

  • Acute transient phlebitis after a morphine infusion
    Alexandros Makris, MD, PhD, MSc, Alexandros Nikas, MD and Anastasios Bontozis, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 734-735; DOI: https://doi.org/10.3949/ccjm.92a.25007

    Prominent ascending erythema outlining the infused vein and its proximal branches developed quickly after infusion.

  • Finding the cause of severe hypokalemia: A 4-step approach
    Finding the cause of severe hypokalemia: A 4-step approach
    Enmanuel A. Leiva-Murillo, MD, Erwin Bechtold-Javier, MD, Pol Candela-Parrilla, MD and Ana Matas-García, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 748-756; DOI: https://doi.org/10.3949/ccjm.92a.25055

    This case illustrates the approach to a group of conditions associated with hypokalemia that usually pose a diagnostic challenge.

  • Barriers to cancer screening in transgender women
    Maryam Sattari, MD, MS
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 721; DOI: https://doi.org/10.3949/ccjm.92c.12001
  • Corticosteroids in severe community-acquired pneumonia
    Enmanuel A. Leiva-Murillo, MD and Rosanel Amaro-Rodríguez, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 723-724; DOI: https://doi.org/10.3949/ccjm.92c.12005
  • Should I consider low-dose rivaroxaban (2.5 mg) for my patient with peripheral artery disease?
    Pranay Marlecha, MD, Deborah Hornacek, MD and Pulkit Chaudhury, MD, MS
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 742-744; DOI: https://doi.org/10.3949/ccjm.92a.25065

    For patients with high ischemic risk, rivaroxaban 2.5 mg twice daily with aspirin 81 or 100 mg daily is a proven strategy to reduce major cardiovascular and limb events.

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