Latest Articles
- Recreational cannabis legalization: Potential implications for individual and community health
The authors discuss evidence on the effects of legalized recreational cannabis on overall cannabis consumption, crime, traffic safety, and individual and community health.
- Managing noninsulin glucose-lowering medications before surgery: A comparison of clinical practice guidelines
Recommendations for adjusting the treatment regimen of each class of noninsulin glucose-lowering agents before surgery are discussed.
- Odontogenic cutaneous fistula
A 55-year-old woman with a history of systemic lupus erythematosus and secondary Sjögren syndrome presented with a 2-year history of facial swelling and intermittent drainage from a skin lesion on her left jaw.
- Immunotherapy meets William Shakespeare
Immune checkpoint inhibitors are potentially life-saving therapies that can trigger a wide range of autoimmune pathology.
IgA nephropathy: Update on pathogenesis and treatmentRenin-angiotensin-aldosterone system inhibitors or corticosteroids remain the cornerstone of therapy, but new agents targeting the different “hits” in the pathogenesis of IgA nephropathy are being introduced.
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
