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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • Fecal microbiota transplantation: Current evidence and future directions
    You have access
    Fecal microbiota transplantation: Current evidence and future directions
    Michael Cymbal, DO, Arjun Chatterjee, MD and Brian Baggott, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 421-428; DOI: https://doi.org/10.3949/ccjm.92a.24107

    Fecal microbiota transplantation is recognized for effectively treating recurrent Clostridioides difficile infection, prompting further investigation into its other possible clinical applications.

  • You have access
    Recreational cannabis legalization: Potential implications for individual and community health
    Taseen Alam, BA, Connor Riegal, BS, Natalie Saadeh, MD, Fernanda Gushken, MD, MS, Hannah Snyder, MD, Brenden Jenks, MD and Akhil Anand, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 407-413; DOI: https://doi.org/10.3949/ccjm.92a.24086

    The authors discuss evidence on the effects of legalized recreational cannabis on overall cannabis consumption, crime, traffic safety, and individual and community health.

  • You have access
    Managing right ventricular failure in the setting of pulmonary embolism
    Anup Katyal, MD and Ashwani Joshi, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 396; DOI: https://doi.org/10.3949/ccjm.92c.07003
  • You have access
    Managing noninsulin glucose-lowering medications before surgery: A comparison of clinical practice guidelines
    Oscar L. Morey-Vargas, MD, Mona Gossmann, MD, Jeffrey M. Ketz, PharmD and Basem B. Abdelmalak, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 429-437; DOI: https://doi.org/10.3949/ccjm.92a.24118

    Recommendations for adjusting the treatment regimen of each class of noninsulin glucose-lowering agents before surgery are discussed.

  • You have access
    Odontogenic cutaneous fistula
    Sagar Khanna, BDS, DDS
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 399-400; DOI: https://doi.org/10.3949/ccjm.92a.24096

    A 55-year-old woman with a history of systemic lupus erythematosus and secondary Sjögren syndrome presented with a 2-year history of facial swelling and intermittent drainage from a skin lesion on her left jaw.

  • You have access
    Immunotherapy meets William Shakespeare
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 390-391; DOI: https://doi.org/10.3949/ccjm.92b.07025

    Immune checkpoint inhibitors are potentially life-saving therapies that can trigger a wide range of autoimmune pathology.

  • You have access
    My adult patient’s hypercholesterolemia is not responding to statins—what’s next?
    Faaiq N. Aslam, MD, Mohamed G. Ibrahim, DO and Razvan Chirila, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 347-351; DOI: https://doi.org/10.3949/ccjm.92a.24117

    Further investigation is needed when patients do not meet their target low-density lipoprotein cholesterol levels with statin therapy alone.

  • You have access
    Nitrogen: The unsung hero of vascular physiology
    Adam J. Brown, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 344-346; DOI: https://doi.org/10.3949/ccjm.92a.24120

    The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.

  • IgA nephropathy: Update on pathogenesis and treatment
    You have access
    IgA nephropathy: Update on pathogenesis and treatment
    Seshma Ramsawak, MD, Scott Cohen, MD, Andrea Linares, DO and Corey Cavanaugh, DO
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 373-383; DOI: https://doi.org/10.3949/ccjm.92a.24105

    Renin-angiotensin-aldosterone system inhibitors or corticosteroids remain the cornerstone of therapy, but new agents targeting the different “hits” in the pathogenesis of IgA nephropathy are being introduced.

  • You have access
    Severe cutaneous reaction induced by allopurinol
    Pietro Bocchi, MD, Lorenza Terroni, MD and Corrado Pattacini, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 331-333; DOI: https://doi.org/10.3949/ccjm.92a.24063

    Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.

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