Latest Articles
IgA nephropathy: Update on pathogenesis and treatmentRenin-angiotensin-aldosterone system inhibitors or corticosteroids remain the cornerstone of therapy, but new agents targeting the different “hits” in the pathogenesis of IgA nephropathy are being introduced.
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
- Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?
The decision hinges on the subtype of pulmonary hypertension the patient has.
- Amoxicillin rash in infectious mononucleosis
A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.
- The gift of lasting immunity
Measles vaccine–induced immunity, although not necessarily lifelong for all individuals, is quite durable.
- Alpha-gal syndrome: Recognizing and managing a tick-bite–related meat allergy
Alpha-gal syndrome is an emerging allergic condition in which immunoglobulin E–mediated symptoms are triggered a few hours after an affected person consumes mammalian meat.
- Managing right ventricular failure in the setting of pulmonary embolism
The authors review current management strategies, including medical, percutaneous interventional, and surgical options, and discuss recent advances in the field.
- The beat goes on: Highlights from the new American and European A-fib guidelines
The authors discuss and compare the latest atrial fibrillation guidelines from American and European medical societies.
- What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
Computed tomography of the patient’s chest is indicated based on the robust association between clubbing and intrathoracic malignancy.
