Latest Articles

  • Capsule endoscopy in gastrointestinal disease: Evaluation, diagnosis, and treatment
    Basil Akpunonu, MD, Jeannine Hummell, CNP, Joseph D. Akpunonu and Shahab Ud Din, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 200-211; DOI: https://doi.org/10.3949/ccjm.89a.20061

    The procedure is mainly used to evaluate obscure bleeding in the small bowel, but it is also used in the evaluation and diagnosis of a wide range of gastrointestinal conditions.

  • Oral hyperpigmentation with weakness and salt-craving
    Joseph Zhou, MD and S. Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 180-181; DOI: https://doi.org/10.3949/ccjm.89a.21036

    The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.

  • Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Tarek Souaid, MD, Jonathan Taliercio, DO, James F. Simon, MD, MBA, Ali Mehdi, MD, MEd and Georges N. Nakhoul, MD, MEd
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 212-222; DOI: https://doi.org/10.3949/ccjm.89a.21100

    A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.

  • Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

  • The devil is in the details: Approach to refractory hypokalemia
    Carmen Elena Cervantes, MD, Karthik Meiyappan Udayappan, MD and Duvuru Geetha, MBBS, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 182-188; DOI: https://doi.org/10.3949/ccjm.89a.21013

    The authors illustrate a stepwise approach to the evaluation of acid-base disturbances.

  • Glycemic targets in the ICU: A look back, and ahead
    Keren Zhou, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 189-190; DOI: https://doi.org/10.3949/ccjm.89a.21127

    Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.

  • Unilateral pulmonary edema
    Yoshihiro Harano, MD and Mikio Nakajima, MD, MPH, PhD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 124-125; DOI: https://doi.org/10.3949/ccjm.89a.21046

    Three weeks after discharge from hospitalization for COVID-19, the patient noted progressively worsening exertional dyspnea and fatigue.

  • Breast cancer risk evaluation for the primary care physician
    Christine L. Klassen, MD, Elizabeth Gilman, MD, Aparna Kaur, MD, Sara P. Lester, MD and Sandhya Pruthi, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 139-146; DOI: https://doi.org/10.3949/ccjm.89a.21023

    The authors offer a systematic approach to the assessment and management of patients at risk of breast cancer.

  • Does my patient need an allergy evaluation for penicillin allergy?
    Jennifer A. Ohtola, MD, PhD and Sandra J. Hong, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 126-129; DOI: https://doi.org/10.3949/ccjm.89a.21004

    In patients with reported penicillin allergy, obtaining a detailed allergy history directly from the patient is the essential first step.

  • Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Yeonsoo Sara Lee, BS, Christopher Wie, MD, Scott Pew, MD and Juliana M. Kling, MD, MPH
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 147-153; DOI: https://doi.org/10.3949/ccjm.89a.21032

    Hormone therapy is the mainstay of treatment, but there is a clear need for safe and effective nonhormonal options. The authors review data on the use of stellate ganglion block in perimenopausal and postmenopausal patients.

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