Latest Articles
- Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease?
These conditions often co-exist and can have complex interactions. The progression of kidney disease increases the risk of major adverse cardiovascular events.
- Evaluating a low anion gap: A practical approach
In teaching and in practice, little attention is given to a low anion gap, an oversight that can result in a missed opportunity to diagnose acute or chronic disorders requiring treatment.
- Should midodrine be used as an intravenous vasopressor-sparing agent in septic shock?
Research and robust data are still lacking regarding use of midodrine in this setting.
- vOka vaccine-associated disseminated varicella zoster
The patient had received the live attenuated vaccine 1 month before presentation. He had no history of varicella infection.
- Should you use compression duplex ultrasonography to detect deep vein thrombosis to evaluate unexplained fevers?
The authors provide recommendations on when to order imaging of the extremities in the evaluation of hospitalized patients with unexplained fever.
- A useful gap
A very low anion gap can suggest a laboratory measurement error or provide a clue to clinically important protein abnormalities or ingestions that warrant specific investigation.
- Mpox: Keep it on the differential
During its current global outbreak, mpox has exhibited novel features that clinicians should be aware of to aid recognition.
- Persistent rectal pain leading to diffuse pustules
The authors relate the workup of a 34-year-old patient with a history of syphilis and human immunodeficiency virus.
- Born again: The many lives of metformin
Repurposing old drugs for new indications is not a new drug-development strategy.

