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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • Acute respiratory distress syndrome: Why a definition matters
    You have access
    Acute respiratory distress syndrome: Why a definition matters
    Christine Girard, MD, Divyajot Sadana, MD, Shewit Giovanni, MD, MS, Heather Torbic, PharmD, BCPS, BCCCP and Abhijit Duggal, MD, MPH, MSc
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 565-571; DOI: https://doi.org/10.3949/ccjm.92a.24115

    The new definition brings acute respiratory distress syndrome into the realm of physicians working on hospital general medicine wards.

  • You have access
    Half-moccasin distribution of acute tinea pedis
    Yusuke Ito, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 529-530; DOI: https://doi.org/10.3949/ccjm.92a.24085

    An 84-year-old woman presented with a week-long history of pruritus on the sole of her right foot.

  • You have access
    Benzodiazepines: Caught between patient needs and guidelines
    Jasleen Kaur, MD, Vania Modesto-Lowe, MD, MPH and Margaret M. Chaplin, MD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 531-535; DOI: https://doi.org/10.3949/ccjm.92a.25019

    Negative sentiment about benzodiazepines has intensified in recent years, and there is increasing emphasis on deprescribing even for people who have had no ill effects from them.

  • You have access
    Collaborative musculoskeletal care: The role for chiropractors
    Samuel M. Schut, DC, Logan J. Benjamin, DC, MPH and Timothy J. Williamson, DC, MS
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 550-554; DOI: https://doi.org/10.3949/ccjm.92a.25014

    Integrating chiropractors into multidisciplinary care settings can help support guideline-concordant care and may free up internists to see more patients with other problems.

  • You have access
    Flexibility is warranted in applying prescribing guidelines
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 520-521; DOI: https://doi.org/10.3949/ccjm.92b.09025

    Discontinuation of benzodiazepines in chronic users may be associated with a small increase in mortality and a higher risk of adverse events, especially in the short term after cessation.

  • You have access
    An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel
    Rujuta Takalkar, BS, Andrea Lorenzo, MD, MS and Suneela Vegunta, MD, NCMP
    Cleveland Clinic Journal of Medicine September 2025, 92 (9) 572-576; DOI: https://doi.org/10.3949/ccjm.92a.24108

    Oral norgestrel, the first daily oral contraceptive pill available over the counter in the United States, is a safe, effective addition to existing over-the-counter contraceptive options.

  • You have access
    Newer diabetes drugs: Surprising shared benefits and unique side effects
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 457-458; DOI: https://doi.org/10.3949/ccjm.92b.08025

    The shared beneficial effects of the SGLT2 inhibitors and the GLP-1 receptor agonists, drugs with distinct mechanisms of action, may have an anti-inflammatory explanation.

  • You have access
    Refractory granuloma annulare
    Mery Deeb, MD and Hadeel Zainah, MD
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 461; DOI: https://doi.org/10.3949/ccjm.92a.24043

    A 77-year-old woman presented with a rash characterized by orange-yellow papules coalescing into erythematous annular plaques on her hands, trunk, and legs.

  • You have access
    Managing the side effects of sodium-glucose cotransporter-2 inhibitors
    Nandan Kodur, BS, Betemariam Sharew, BA, M. Cecilia Lansang, MD, MPH and W. H. Wilson Tang, MD
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 503-511; DOI: https://doi.org/10.3949/ccjm.92a.24071

    The authors review recent evidence on the side effects of sodium-glucose cotransporter-2 inhibitors and corresponding strategies for preventing and managing them.

  • You have access
    The overlooked and undertreated perils of premature ovarian insufficiency
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 475-482; DOI: https://doi.org/10.3949/ccjm.92gr.25056

    Physicians should be alert to the possibility of undiagnosed premature ovarian insufficiency—loss of ovarian function before age 40—and know what to do if the condition is suspected.

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