Latest Articles
- Interpreting the DIGIT-HF trial: Time for a new look at digitalis?
Digitoxin reduced the risk of death or first hospitalization for heart failure in patients with symptomatic heart failure with reduced ejection fraction who were already being treated with guideline-directed medical therapy.
- A 24-year-old man with severe hemolytic anemia and variable Coombs test results
The patient was admitted to the hospital because of dark urine, jaundice, fatigue, and confusion.
- Getting stuck on a name: An example of an eponymous syndrome
Debate continues about whether we should continue to use eponymous diagnostic nomenclature or shift entirely to an anatomic or pathophysiologic descriptive terminology.
- ‘Boxing glove’ hands in a patient initially diagnosed with RS3PE syndrome
The patient had edema that limited finger flexion, impairing daily tasks such as putting on socks.
- Alpha-1 antitrypsin deficiency: A persistently underrecognized condition
Detecting alpha-1 antitrypsin deficiency early is imperative because diagnostic delay is associated with harm, including worsened clinical status and impaired survival.
- Optimizing bowel preparation for colonoscopy: Updated consensus recommendations
Key updates in the 2025 guideline include simplifying dietary restrictions to low-residue foods for a single day before colonoscopy, preferring 2-L over 4-L preparation regimens, and universally recommending split-dose administration.
- Westermark sign (focal oligemia) in pulmonary embolism
The patient’s chest radiograph showed a focal area of reduced blood flow in the middle and upper zones of the right lung.
- Ogilvie syndrome (colonic pseudo-obstruction)
Two days after the patient underwent surgery to repair a left femur fracture, his abdomen became markedly distended, but without pain.
Polycystic ovary syndrome: An update on diagnosis and managementBecause this syndrome affects health throughout the lifespan, long-term management is essential, not only to control symptoms but also to prevent associated metabolic conditions.
