Latest Articles
- Should potassium-competitive acid blockers replace proton pump inhibitors as first-line therapy for patients with severe (Los Angeles grade C or D) esophagitis?
Potassium-competitive acid blockers are reserved for patients who cannot tolerate proton pump inhibitors or who do not respond to them.
- Preventing cirrhosis: Why primary care clinicians should screen for liver disease in patients who drink heavily
Clinicians in the primary care setting can identify patients with heavy alcohol use and alcohol-related liver disease before they develop advanced liver damage.
- Profound xanthomas in a young man
The patient had a history of type 2 diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia, with a fasting serum triglyceride level of 9,000 mg/dL.
- Xanthomas: A clue to undiagnosed lipid disorders
Given the wide availability of direct-to-consumer laboratory testing, it is reasonable to ask whether a working knowledge of xanthomas still matters for trainees and clinicians.
- A new direction in pain management?
It would be nice to have a treatment option for pain that is less limited by side effects, cognitive dysfunction, addiction potential, and red tape.
Right ventricular failure in a young manThe patient initially experienced dyspnea only on exertion, but over the 2 months before presentation it had progressed to shortness of breath at rest.
- Suzetrigine: A novel nonopioid systemic analgesic
The systemic sodium channel blocker suzetrigine may serve as another option for multimodal postoperative analgesia regimens and for managing acute nonsurgical pain.
- Rapidly progressive kidney failure in an 82-year-old man with respiratory symptoms
The patient presented to the emergency department due to worsening dry cough, lower-extremity edema, and fatigue, all of which had begun about 2 weeks earlier.
- Artificial intelligence in medicine: How it works, how it fails
Using practical clinical examples, the authors explain the subset of artificial intelligence called large language models, highlighting the capabilities and limitations of these systems.
