Latest Articles

  • Respiratory virus season: Strategies for successful navigation
    Pooja Cerrato, PharmD, BCPS and Steven Mawhorter, MD, DTM&H
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 95-102; DOI: https://doi.org/10.3949/ccjm.92a.24103

    The authors review the burden, prevention, diagnosis, and treatment of influenza, COVID-19, and respiratory syncytial virus infection.

  • Wolff-Parkinson-White syndrome: Diagnostic and management strategies
    Masihullah Barat, MD, David Torres Barba, MD, PhD and Gordon Ho, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 119-127; DOI: https://doi.org/10.3949/ccjm.92a.24059

    The challenge lies in managing those with the Wolff-Parkinson-White pattern on electrocardiogram but no symptoms.

  • Thyroid obstacle course: Many challenges from a single gland
    Timothy W. Bodnar, MD and Sima Saberi, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 87-93; DOI: https://doi.org/10.3949/ccjm.92a.24076

    The patient presented to his primary care clinician for new irritability, anxiety, and insomnia. Laboratory testing revealed a low thyroid-stimulating hormone level.

  • Don’t judge a book by its cover: Unusual presentations of pericardial disease
    Don’t judge a book by its cover: Unusual presentations of pericardial disease
    William A. Schiavone, DO and David S. Majdalany, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 109-116; DOI: https://doi.org/10.3949/ccjm.92a.24065

    Taking a good history, performing a good physical examination, and properly reading an electrocardiogram and chest radiograph are the best starting points for diagnosing pericardial and mediastinal disease.

  • Treating the thyroid: Trust the feedback loop
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 71-72; DOI: https://doi.org/10.3949/ccjm.92b.02025

    Studies show that, when testing to detect or monitor thyroid dysfunction, we order more free T3 and T4 levels than are necessary. We apparently should trust the thyroid-stimulating hormone feedback loop more than we do.

  • Vesicular pityriasis rosea
    Xiaobei Liu, MD, PhD, Lizhi Ma, MD, Peimei Zhou, MD, PhD and Tao Chen, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 81-82; DOI: https://doi.org/10.3949/ccjm.92a.24004

    A 37-year-old man presented with a 9-day history of disseminated pruritic rash on his trunk and extremities.

  • Our Peer-Reviewers for 2024
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 79;
  • Classic diabetic ketoacidosis and the euglycemic variant: Something old, something new
    Adi E. Mehta, MD and Robert Zimmerman, MD
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 33-39; DOI: https://doi.org/10.3949/ccjm.92a.24075

    The authors review differences in the pathophysiology and management of classic diabetic ketoacidosis and the euglycemic variant, the latter of which has become more common with the increasing use of sodium-glucose cotransporter 2 inhibitors.

  • How can I better recognize and manage delirium in my hospitalized patients?
    Amanda Pomerantz, DO, Anna P. Shapiro-Krew, MD and Andrew Coulter, MD, MA
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 17-20; DOI: https://doi.org/10.3949/ccjm.92a.24048

    By knowing common precipitants and mimickers of delirium and considerations for workup, clinicians can implement nonpharmacologic preventive strategies, better identify patients experiencing delirium, and optimize symptom management.

  • Sleep is like Rodney Dangerfield
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 9-10; DOI: https://doi.org/10.3949/ccjm.92b.01025

    Sleep quantity (and, in some cases, quality) has been shown to impact memory and learning, mood, appetite, and pain, yet many patients and clinicians do not give sleep the respect it deserves.

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