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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • You have access
    Newer diabetes drugs: Surprising shared benefits and unique side effects
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 457-458; DOI: https://doi.org/10.3949/ccjm.92b.08025

    The shared beneficial effects of the SGLT2 inhibitors and the GLP-1 receptor agonists, drugs with distinct mechanisms of action, may have an anti-inflammatory explanation.

  • You have access
    Odontogenic cutaneous fistula
    Sagar Khanna, BDS, DDS
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 399-400; DOI: https://doi.org/10.3949/ccjm.92a.24096

    A 55-year-old woman with a history of systemic lupus erythematosus and secondary Sjögren syndrome presented with a 2-year history of facial swelling and intermittent drainage from a skin lesion on her left jaw.

  • You have access
    Immunotherapy meets William Shakespeare
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 390-391; DOI: https://doi.org/10.3949/ccjm.92b.07025

    Immune checkpoint inhibitors are potentially life-saving therapies that can trigger a wide range of autoimmune pathology.

  • You have access
    In Reply: Managing right ventricular failure in the setting of pulmonary embolism
    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 396-397; DOI: https://doi.org/10.3949/ccjm.92c.07004
  • You have access
    Most elderly patients with subclinical hypothyroidism do not need to be treated
    Scott Selinger, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 395; DOI: https://doi.org/10.3949/ccjm.92c.07001
  • You have access
    In Reply: Most elderly patients with subclinical hypothyroidism do not need to be treated
    Risheng Xu, DO, Nicola Abate, MD, Nalini Ram, MD and Kristina Little, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 395; DOI: https://doi.org/10.3949/ccjm.92c.07002
  • You have access
    Breast cancer risk and screening for transgender and gender-diverse individuals
    CME article
    Dzhuliyan V. Vasilev, MD, MMSc, Juliana M. Kling, MD, MPH and Evelyn F. Carroll, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 439-447; DOI: https://doi.org/10.3949/ccjm.92a.24088

    Evidence on breast cancer risk in transgender and gender-diverse individuals is limited, and recent guidelines are primarily based on expert consensus, retrospective cohort studies, and extrapolation from cisgender populations.

  • You have access
    Insights from the LAAOS III trial of left atrial appendage occlusion to prevent stroke in atrial fibrillation
    Anže Djordjević, MD, PhD and Edward Soltesz, MD, MPH
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 415-419; DOI: https://doi.org/10.3949/ccjm.92a.25001

    Left atrial appendage occlusion added to routine cardiac surgery reduced the risk of ischemic stroke or systemic embolism in patients with atrial fibrillation and high stroke risk, but questions remain.

  • You have access
    How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?
    Rupayan Kundu, MD, Arjun Chatterjee, MD, Jessica Philpott, MD, PhD and Lucy Boyce Kennedy, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 401-405; DOI: https://doi.org/10.3949/ccjm.92a.24090

    Diarrhea and colitis, which can result from infection or be complications of immune checkpoint inhibitors, require prompt evaluation so that appropriate treatment can be started.

  • Fecal microbiota transplantation: Current evidence and future directions
    You have access
    Fecal microbiota transplantation: Current evidence and future directions
    Michael Cymbal, DO, Arjun Chatterjee, MD and Brian Baggott, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 421-428; DOI: https://doi.org/10.3949/ccjm.92a.24107

    Fecal microbiota transplantation is recognized for effectively treating recurrent Clostridioides difficile infection, prompting further investigation into its other possible clinical applications.

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