Latest Articles

  • Preventing cirrhosis: Why primary care clinicians should screen for liver disease in patients who drink heavily

    Pranay Nadella, MD, MPhil, Esperance Schaefer, MD, MPH and Clare Landefeld, MD, MS
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 88-93;
    • DOI: https://doi.org/10.3949/ccjm.93a.25045

    • Clinicians in the primary care setting can identify patients with heavy alcohol use and alcohol-related liver disease before they develop advanced liver damage.

  • Xanthomas: A clue to undiagnosed lipid disorders

    Ashish Sarraju, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 76-77;
    • DOI: https://doi.org/10.3949/ccjm.93a.25116

    • Given the wide availability of direct-to-consumer laboratory testing, it is reasonable to ask whether a working knowledge of xanthomas still matters for trainees and clinicians.

  • Suzetrigine: A novel nonopioid systemic analgesic

    Anthony E. Divito, MD, Matthew Sharobeem, DO, Gausan R. Bajracharya, MD and Basem B. Abdelmalak, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 94-98;
    • DOI: https://doi.org/10.3949/ccjm.93a.25087

    • The systemic sodium channel blocker suzetrigine may serve as another option for multimodal postoperative analgesia regimens and for managing acute nonsurgical pain.

  • Rapidly progressive kidney failure in an 82-year-old man with respiratory symptoms

    CME Image
    Bernardo Henrique Mendes Correa, MD, Ali Mushtaq, MD, Ali Awada, Faiz Anwer, MD and Anam Ashfaque, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 99-105;
    • DOI: https://doi.org/10.3949/ccjm.93a.25037

    • The patient presented to the emergency department due to worsening dry cough, lower-extremity edema, and fatigue, all of which had begun about 2 weeks earlier.

  • Should potassium-competitive acid blockers replace proton pump inhibitors as first-line therapy for patients with severe (Los Angeles grade C or D) esophagitis?

    Sandra Elmasry, MD, Allon Kahn, MD, Lisa Marks, MLS, AHIP and Neera Agrwal, MD, PhD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 84-87;
    • DOI: https://doi.org/10.3949/ccjm.93a.25044

    • Potassium-competitive acid blockers are reserved for patients who cannot tolerate proton pump inhibitors or who do not respond to them.

  • Profound xanthomas in a young man

    Lex Leonhardt, DO and Natallia Maroz, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 73-75;
    • DOI: https://doi.org/10.3949/ccjm.93a.24093

    • The patient had a history of type 2 diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia, with a fasting serum triglyceride level of 9,000 mg/dL.

  • TOC Icon

    Right ventricular failure in a young man

    Keerthana Sankar, MD and Yuri Matusov, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 106-112;
    • DOI: https://doi.org/10.3949/ccjm.93a.25048

    • The patient initially experienced dyspnea only on exertion, but over the 2 months before presentation it had progressed to shortness of breath at rest.

  • Our Peer Reviewers for 2025

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 71;

  • Artificial intelligence in medicine: How it works, how it fails

    Rick Rejeleene, PhD and Neil B. Mehta, MBBS, MS
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 113-120;
    • DOI: https://doi.org/10.3949/ccjm.93a.25089

    • Using practical clinical examples, the authors explain the subset of artificial intelligence called large language models, highlighting the capabilities and limitations of these systems.

  • A new direction in pain management?

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 67-68;
    • DOI: https://doi.org/10.3949/ccjm.93b.02026

    • It would be nice to have a treatment option for pain that is less limited by side effects, cognitive dysfunction, addiction potential, and red tape.

Previous
Next