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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

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    Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
    Nandan Kodur, BS and W. H. Wilson Tang, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 673-675; DOI: https://doi.org/10.3949/ccjm.92a.25078

    The authors discuss 3 unresolved questions about de-escalating and escalating guideline-directed medical therapy in patients with improved ejection fraction.

  • You have access
    Teprotumumab for thyroid eye disease: A reality check
    Julian Perry, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 702-703; DOI: https://doi.org/10.3949/ccjm.92a.25066

    Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.

  • You have access
    Managing obesity in older adults
    CME article
    Shyam Sundaresh, MD, Sara Saliba, MD, RD, Farah Ziyadeh, MD, Yael Mauer, MD, MPH and Willy Marcos Valencia, MD, MSc
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 686-692; DOI: https://doi.org/10.3949/ccjm.92a.24094

    The goals of treating obesity in older adults are to ease its complications and improve functional status and quality of life, with or without weight loss.

  • You have access
    Chronic ocular pain
    Radhika S. Amin, Eliot N. Haddad and Rony R. Sayegh, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 652; DOI: https://doi.org/10.3949/ccjm.92c.11003
  • You have access
    Failure to thrive in hospitalized older adults: More than a ‘social admission’
    Shoshana Streiter, MD and Samir Tulebaev, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 662-666; DOI: https://doi.org/10.3949/ccjm.92a.25033

    Failure to thrive documented as an admitting diagnosis presents an opportunity to identify, articulate, and begin to ameliorate the true underlying causes of the patient’s health deficits.

  • You have access
    What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
    Dewonna Ferguson, MD, MSCP, Suneela Vegunta, MD, MSCP and Sara Shihab, MD, MSCP
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 676-678; DOI: https://doi.org/10.3949/ccjm.92a.24116

    Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.

  • You have access
    In Reply: Managing noninsulin glucose-lowering medications before surgery
    Oscar L. Morey-Vargas, MD, Mona Gossmann, MD, Jeffrey M. Ketz, PharmD and Basem B. Abdelmalak, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 651-652; DOI: https://doi.org/10.3949/ccjm.92c.11002
  • Lipoprotein(a) in clinical practice: What clinicians need to know
    You have access
    Lipoprotein(a) in clinical practice: What clinicians need to know
    Astefanos Al-Dalakta, MD, Leslie S. Cho, MD and Ashish Sarraju, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 679-685; DOI: https://doi.org/10.3949/ccjm.92a.25020

    Elevated lipoprotein(a) by itself is not an indication for statin therapy, but its presence supports earlier or more aggressive preventive therapy.

  • You have access
    Thyroid eye disease: What’s the latest?
    CME article
    Ashley B. Vincent, DO, Alexander R. Engelmann, MD, Catherine J. Hwang, MD and Christian Nasr, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 693-701; DOI: https://doi.org/10.3949/ccjm.92a.25043

    A better understanding of the pathophysiology of this autoimmune disorder has led to innovative insights into its treatment, but long-term management remains a challenge.

  • Low-dose colchicine for management of coronary artery disease
    You have access
    Low-dose colchicine for management of coronary artery disease
    Abhayjit Singh, MD, Vikas Sunder, MD and Leslie Cho, MD
    Cleveland Clinic Journal of Medicine October 2025, 92 (10) 609-618; DOI: https://doi.org/10.3949/ccjm.92a.25005

    Current guidelines endorse adding low-dose colchicine to standard medical therapy for coronary artery disease prevention, but data show clinicians remain hesitant to use it for this indication.

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