Latest Articles
- Should potassium-competitive acid blockers replace proton pump inhibitors as first-line therapy for patients with severe (Los Angeles grade C or D) esophagitis?
Potassium-competitive acid blockers are reserved for patients who cannot tolerate proton pump inhibitors or who do not respond to them.
- A new direction in pain management?
It would be nice to have a treatment option for pain that is less limited by side effects, cognitive dysfunction, addiction potential, and red tape.
- Suzetrigine: A novel nonopioid systemic analgesic
The systemic sodium channel blocker suzetrigine may serve as another option for multimodal postoperative analgesia regimens and for managing acute nonsurgical pain.
- Teprotumumab for thyroid eye disease: A reality check
Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.
- Thyroid eye disease: What’s the latest?
A better understanding of the pathophysiology of this autoimmune disorder has led to innovative insights into its treatment, but long-term management remains a challenge.
- Optimizing hypertension treatment: Evidence-based approaches and new drugs
The authors discuss current evidence-based approaches to managing hypertension and optimizing blood pressure control through a series of cases representing common clinical scenarios.
- Benzodiazepines: Caught between patient needs and guidelines
Negative sentiment about benzodiazepines has intensified in recent years, and there is increasing emphasis on deprescribing even for people who have had no ill effects from them.
- Flexibility is warranted in applying prescribing guidelines
Discontinuation of benzodiazepines in chronic users may be associated with a small increase in mortality and a higher risk of adverse events, especially in the short term after cessation.
- An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel
Oral norgestrel, the first daily oral contraceptive pill available over the counter in the United States, is a safe, effective addition to existing over-the-counter contraceptive options.