Latest Articles

  • Peripheral artery disease: Putting the updated 2024 AHA/ACC guideline into practice

    CME Image
    Pavel Kibrik, DO, Enrico Prajiante Bertolino, MD, Sasan Partovi, MD, G. Jay Bishop, MD, Aravinda Nanjundappa, MD and Lee Kirksey, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 603-615;
    • DOI: https://doi.org/10.3949/ccjm.93a.25101
    • The new guideline, which updates the 2016 guideline, clarifies clinical terminology, applies trial evidence to pharmacotherapy and revascularization recommendations, and addresses equity and access to care.

  • How can I differentiate delirium from altered mental status in hospitalized older adults?

    Asim Kichloo, MD, Calista Hemarga, BS, Ivan Magallanes Marrufo, MPH and Sandra Davis, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 581-585;
    • DOI: https://doi.org/10.3949/ccjm.93a.26025
    • Bedside screening tools can be used to distinguish delirium from other causes of altered mental status, enabling timely care and reducing costs.

  • How should I evaluate allergic disease in patients with asthma?

    Alejandro Chapa-Rodriguez, MD and Jennifer Tartaglia, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 586-588;
    • DOI: https://doi.org/10.3949/ccjm.93a.25119
    • Indiscriminate testing can lead to misinterpretation of results, unnecessary escalation of therapy, and increased cost without clinical benefit.

  • A historical irony—quantitative measurement in critically ill patients is not a panacea

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 575-576;
    • DOI: https://doi.org/10.3949/ccjm.93b.10026
    • Some diagnostic tools that were supposed to render the bedside examination less relevant have themselves failed the test of necessity; meanwhile, the bedside skills they supposedly would displace have also atrophied.

  • Immunoglobulin E: From horses to myeloma

    Adam J. Brown, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 589-591;
    • DOI: https://doi.org/10.3949/ccjm.93a.26078
    • The author explores how IgE was discovered, the challenges researchers faced when isolating the antibody, and the connection among IgE, mast cells, and histamine.

  • Painless sternoclavicular osteitis in fever of unknown origin: A clue to probable SAPHO syndrome

    Taisuke Kamiyoshikawa, MD, Kensaku Shojima, MD, PhD, Yoshihiro Wada, MD, PhD, Hiromitsu Yamazaki, MD, PhD, Yasuyuki Nagasawa, MD, PhD and Ken Shinmura, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 578-580;
    • DOI: https://doi.org/10.3949/ccjm.93a.25110
    • After more than 1 month of acetaminophen, the patient continued to have fever and elevated inflammatory markers.

  • Most elderly patients with subclinical hypothyroidism do not need to be treated

    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 623;
  • Interpreting EVERDAC: Deferring arterial cannulation in critically ill patients with shock

    Adrienne K. Ho, MBBS, MSc
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 597-602;
    • DOI: https://doi.org/10.3949/ccjm.93a.25108
    • Results of the EVERDAC trial challenge the strategy of reflexively placing an arterial line when a patient is admitted to the intensive care unit.

  • Acute vertigo in a 67-year-old woman: Peripheral or central?

    David Kweku Aseda Donkor, MD, Kapil Nayar, MD and Jerma Adams, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 592-596;
    • DOI: https://doi.org/10.3949/ccjm.93a.26035
    • The patient presented with dizziness that started earlier that morning when she rose from bed, persisted after she returned to bed, and worsened with head movement.

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    Shedding: An updated guide to a common cause of hair loss

    Wilma F. Bergfeld, MD and Daniela Mendez, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 616-622;
    • DOI: https://doi.org/10.3949/ccjm.93a.26008
    • Telogen effluvium, or hair shedding, results from a temporary disruption of the normal hair growth cycle and typically is reversible.

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