Latest Articles

  • How should I incorporate emergency contraception counseling into my practice?

    Alexa R. Wilden, MD and Heather M. Wainstein, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 738-741;
    • DOI: https://doi.org/10.3949/ccjm.92a.25029
    • Emergency contraception counseling should be provided routinely to women at risk of unintended pregnancy as part of counseling on reproductive goals.

  • How can I select the right thyroid hormone formulation for my patient with hypothyroidism?

    Lea El Hage, MD and Vinni Makin, MBBS, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 745-747;
    • DOI: https://doi.org/10.3949/ccjm.92a.25042
    • Knowing the features of the available thyroid hormone formulations can provide a starting point for individualizing therapy for patients who have concerns about product formulations or remain symptomatic despite a normal thyroid-stimulating hormone level.

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    Finding the cause of severe hypokalemia: A 4-step approach

    Enmanuel A. Leiva-Murillo, MD, Erwin Bechtold-Javier, MD, Pol Candela-Parrilla, MD and Ana Matas-García, MD, PhD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 748-756;
    • DOI: https://doi.org/10.3949/ccjm.92a.25055
    • This case illustrates the approach to a group of conditions associated with hypokalemia that usually pose a diagnostic challenge.

  • Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both

    CME Image
    Michelle D. Lundholm, MD and Keren Zhou, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 757-763;
    • DOI: https://doi.org/10.3949/ccjm.92a.25069
    • Latent autoimmune diabetes in adults shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy.

  • Trident sign in osmotic demyelination syndrome

    Erin Equinozzi, MSc, Clement D. Lee, MD, MSc and Pamela Schaefer, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 732-733;
    • DOI: https://doi.org/10.3949/ccjm.92a.24080
    • Brain magnetic resonance imaging showed a confluent trident-shaped lesion in the central pons 1 week after correction of the patient’s chronic hyponatremia.

  • Skin manifestations of mpox

    James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737;
    • DOI: https://doi.org/10.3949/ccjm.92a.25022
    • The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

  • In Reply: Corticosteroids in severe community-acquired pneumonia

    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, Cody O’Rear, DO and Shraddha Narechania, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 724;
    • DOI: https://doi.org/10.3949/ccjm.92c.12006
  • Acute transient phlebitis after a morphine infusion

    Alexandros Makris, MD, PhD, MSc, Alexandros Nikas, MD and Anastasios Bontozis, MD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 734-735;
    • DOI: https://doi.org/10.3949/ccjm.92a.25007
    • Prominent ascending erythema outlining the infused vein and its proximal branches developed quickly after infusion.

  • Diabetes: Putting off until tomorrow what could happen today can be good

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 715-717;
    • DOI: https://doi.org/10.3949/ccjm.92b.12025
    • Prevention of beta-cell loss and preservation of endogenous insulin production have been attractive treatment prerogatives in type 1 diabetes.

  • In reply: All menopausal hormone therapy is not alike

    Samantha F. Butts, MD, MSCE
    • Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722;
    • DOI: https://doi.org/10.3949/ccjm.92c.12003