Latest Articles
- Nitrogen: The unsung hero of vascular physiology
The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.
IgA nephropathy: Update on pathogenesis and treatmentRenin-angiotensin-aldosterone system inhibitors or corticosteroids remain the cornerstone of therapy, but new agents targeting the different “hits” in the pathogenesis of IgA nephropathy are being introduced.
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
- Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?
The decision hinges on the subtype of pulmonary hypertension the patient has.
- Amoxicillin rash in infectious mononucleosis
A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.
- Does my adult patient need a measles vaccine?
Possibly. Adults without acceptable presumptive evidence of immunity to measles should receive 1 dose of the measles-mumps-rubella vaccine, and 2 doses are recommended for adults in special situations.
- Do I need to treat supine hypertension in my hospitalized patient?
Inpatients with an elevated supine blood pressure should be evaluated for orthostatic changes before treatment is considered.
