Latest Articles

  • Hold ACE inhibitors and ARBs before noncardiac surgery? Emerging evidence suggests a patient-specific approach

    CME Image
    Maureen Keshock, MD, MHSA, Elise Zhang, MS-3, Christopher Whinney, MD and Kenneth C. Cummings III, MD, MS
    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 619-626;
    • DOI: https://doi.org/10.3949/ccjm.92a.25035

    • Judicious withholding of ACE inhibitors and ARBs in vulnerable populations—and promptly resuming them—may strike the safest balance between renal protection and hemodynamic stability.

  • No surprise, all inflammation is not created equal as it relates to cardiovascular disease

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 587-589;
    • DOI: https://doi.org/10.3949/ccjm.92b.10025

    • It is accepted that inflammation is an important component of atherosclerotic cardiovascular disease, but have we found the right inflammatory target for pharmacologic therapy?

  • Do patients with severe community-acquired bacterial pneumonia benefit from systemic corticosteroids?

    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, MSc, MBBCh, Cody O’Rear, DO and Shraddha Narechania, MD
    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 600-604;
    • DOI: https://doi.org/10.3949/ccjm.92a.25023

    • Recent evidence has swung the pendulum back in favor of using corticosteroids in patients with severe community-acquired pneumonia.

  • Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce

    • Cleveland Clinic Journal of Medicine October 2025, 92 (10) 593;

  • An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel

    Rujuta Takalkar, BS, Andrea Lorenzo, MD, MS and Suneela Vegunta, MD, NCMP
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 572-576;
    • DOI: https://doi.org/10.3949/ccjm.92a.24108

    • Oral norgestrel, the first daily oral contraceptive pill available over the counter in the United States, is a safe, effective addition to existing over-the-counter contraceptive options.

  • Optimizing hypertension treatment: Evidence-based approaches and new drugs

    CME Image
    Astefanos Al-Dalakta, MD, Ahmad Ghanem, MD, Chadi Tabaja, MD, Issam Motairek, MD, Abdel Hadi El Hajjar, MD and Luke J. Laffin, MD
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 555-564;
    • DOI: https://doi.org/10.3949/ccjm.92a.24119

    • The authors discuss current evidence-based approaches to managing hypertension and optimizing blood pressure control through a series of cases representing common clinical scenarios.

  • Benzodiazepines: Caught between patient needs and guidelines

    Jasleen Kaur, MD, Vania Modesto-Lowe, MD, MPH and Margaret M. Chaplin, MD
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 531-535;
    • DOI: https://doi.org/10.3949/ccjm.92a.25019

    • Negative sentiment about benzodiazepines has intensified in recent years, and there is increasing emphasis on deprescribing even for people who have had no ill effects from them.

  • Half-moccasin distribution of acute tinea pedis

    Yusuke Ito, MD
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 529-530;
    • DOI: https://doi.org/10.3949/ccjm.92a.24085

    • An 84-year-old woman presented with a week-long history of pruritus on the sole of her right foot.

  • Flexibility is warranted in applying prescribing guidelines

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 520-521;
    • DOI: https://doi.org/10.3949/ccjm.92b.09025

    • Discontinuation of benzodiazepines in chronic users may be associated with a small increase in mortality and a higher risk of adverse events, especially in the short term after cessation.

  • Collaborative musculoskeletal care: The role for chiropractors

    Samuel M. Schut, DC, Logan J. Benjamin, DC, MPH and Timothy J. Williamson, DC, MS
    • Cleveland Clinic Journal of Medicine September 2025, 92 (9) 550-554;
    • DOI: https://doi.org/10.3949/ccjm.92a.25014

    • Integrating chiropractors into multidisciplinary care settings can help support guideline-concordant care and may free up internists to see more patients with other problems.

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