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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • Most elderly patients with subclinical hypothyroidism do not need to be treated
    You have access
    Most elderly patients with subclinical hypothyroidism do not need to be treated
    Risheng Xu, DO, Nicola Abate, MD, Nalini Ram, MD and Kristina Little, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 221-231; DOI: https://doi.org/10.3949/ccjm.92a.24098

    Age-adjusted thyrotropin reference ranges, consideration of individual circumstances, and a wait-and-see approach for mild subclinical hypothyroidism might be more suitable than a universal treatment strategy.

  • You have access
    Psychedelics in the medical toolbox?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 200-201; DOI: https://doi.org/10.3949/ccjm.92b.04025

    Given the historical association of psychedelics as “recreational” mind-altering compounds within countercultures of the 1960s and 1970s, their current introduction into several aspects of medical practice is a surprise to many.

  • You have access
    Should glucagon-like peptide 1 receptor agonists be withheld during the preoperative period?
    Sneha Mishra, MBBS, Patress A. Persons, MD and Sophie Bersoux, MD, MPH
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 209-211; DOI: https://doi.org/10.3949/ccjm.92a.24110

    Clinical judgment should guide this decision, taking into account patient symptoms and the presence of factors that may delay gastric emptying and increase risk for aspiration.

  • You have access
    Subclinical hypothyroidism: What’s in a name?
    Jennifer S. Mammen, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 233-235; DOI: https://doi.org/10.3949/ccjm.92a.25028

    Clinicians should remain thoughtful about the variability in aging biology and not be blinded by a name.

  • You have access
    Psychedelics, spirituality, and existential distress in patients at the end of life
    Nicole Cornish, PharmD, Tara Coles, MD, M. Jennifer Cheng, MD, Claudia Ruiz Sotomayor, MD, DBe, Aaron Wolfgang, MD and Christopher Spevak, MD, MPH, JD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 248-254; DOI: https://doi.org/10.3949/ccjm.92a.24100

    The authors explore the role of psychedelics in addressing patients’ spiritual and existential suffering at the end of life from a medical, ethical, and legal perspective.

  • You have access
    In Reply: Insomnia in older adults
    Margaret M. Chaplain, MD, Roberto León-Barriera, MD and Vania Modesto-Lowe, MD, MPH
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 144; DOI: https://doi.org/10.3949/ccjm.92c.03005
  • You have access
    Classic diabetic ketoacidosis and the euglycemic variant
    Param Darpan Sheth, MBBS
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 142; DOI: https://doi.org/10.3949/ccjm.92c.03002
  • You have access
    Effective but inaccessible antiobesity medications
    Sima Saberi, MD, Sabiha M. Hussain, MD, Mohammad Kazem Fallahzadeh, MD, MAS, Hector Madariaga, MD, Pooja Budhiraja, MBBS and Kenneth J. Woodside, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 141; DOI: https://doi.org/10.3949/ccjm.92c.03001
  • Coronary artery bypass grafting: Practice trends and projections
    You have access
    Coronary artery bypass grafting: Practice trends and projections
    Richard Ramsingh, MD and Faisal G. Bakaeen, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 181-191; DOI: https://doi.org/10.3949/ccjm.92a.23071

    Future directions include expanding the use of multiarterial grafting, offering patients less-invasive approaches, and enhancing operative recovery.

  • You have access
    Can my patient with a ‘sulfa allergy’ receive celecoxib or other nonantimicrobial sulfonamides?
    Nicholas B. Cline, MD, Amudha Pazhanisamy, DO and David M. Lang, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 147-151; DOI: https://doi.org/10.3949/ccjm.92a.24054

    There is no cross-reactivity between antimicrobial and nonantimicrobial sulfonamides, and patients with a history of immunoglobulin E–mediated reaction to a sulfonamide antibiotic can receive nonantimicrobial sulfonamides.

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