Latest Articles

  • A practical guide for buprenorphine initiation in the primary care setting
    Roberto León-Barriera, MD, Samantha Jayne Zwiebel, MD, MA and Vania Modesto-Lowe, MD, MPH
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 557-564; DOI: https://doi.org/10.3949/ccjm.90a.23022

    The authors review changes in prescribing laws and outline buprenorphine induction protocols that can be adopted in the primary care setting.

  • Born again: The many lives of metformin
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 523-524; DOI: https://doi.org/10.3949/ccjm.90b.09023

    Repurposing old drugs for new indications is not a new drug-development strategy.

  • Resistant hypertension: A stepwise approach
    Leslie E. F. Page, DO, MPH
    Cleveland Clinic Journal of Medicine May 2023, 90 (5) 274; DOI: https://doi.org/10.3949/ccjm.90c.05002
  • Resistant hypertension: A stepwise approach
    Yehia Yousri Mishriki, MD
    Cleveland Clinic Journal of Medicine May 2023, 90 (5) 273-274; DOI: https://doi.org/10.3949/ccjm.90c.05001
  • Heart failure with reduced ejection fraction: What’s new in the 2022 guideline?
    Michelle M. Kittleson, MD, PhD
    Cleveland Clinic Journal of Medicine April 2023, 90 (4) 215-220; DOI: https://doi.org/10.3949/ccjm.90a.22101

    Evidence-based and guideline-based medical therapies can help patients feel better, stay out of the hospital, live longer, and potentially improve left ventricular function.

  • Resistant hypertension: A stepwise approach
    Resistant hypertension: A stepwise approach
    Jordana Yahr, DO, George Thomas, MD, Juan Calle, MD and Jonathan J. Taliercio, DO
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 115-125; DOI: https://doi.org/10.3949/ccjm.90a.22046

    The authors review the definition and prevalence of resistant hypertension and its diagnostic workup and management, including lifestyle modifications, drugs, and experimental therapies.

  • Balancing the myths of corticosteroid therapy
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 480-481; DOI: https://doi.org/10.3949/ccjm.89b.09022

    No class of drug has more mythical attributes, interfaces with different medical specialties, or clinical street lore than corticosteroids.

  • Steroids in the acutely ill: Evolving recommendations and practice
    Stephen M. Pastores, MD, MACP, FCCP, FCCM
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 505-511; DOI: https://doi.org/10.3949/ccjm.89gr.22002

    New information has been generated with regard to what causes critical illness-related corticosteroid insufficiency, how to diagnose it, who should receive corticosteroid treatment, and what regimens to use.

  • Managing stage 1 hypertension: Consider the risks, stop the progression
    Abel Hooker, MD, Kevin G. Buda, DO and Maarya Pasha, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 244-248; DOI: https://doi.org/10.3949/ccjm.89a.21101

    Guidelines on managing patients with stage 1 hypertension and a low 10-year risk of atherosclerotic cardiovascular disease.

  • Psychogenic nonepileptic seizure: A neurologist’s perspective
    Elaine Wyllie, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 260-261; DOI: https://doi.org/10.3949/ccjm.89a.21129

    Confirming the diagnosis is only the start of the journey. The greater challenge and opportunity lie in how physicians present the diagnosis to the patient and family.

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