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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Latest Articles

  • You have access
    Diabetes: Putting off until tomorrow what could happen today can be good
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 715-717; DOI: https://doi.org/10.3949/ccjm.92b.12025

    Prevention of beta-cell loss and preservation of endogenous insulin production have been attractive treatment prerogatives in type 1 diabetes.

  • You have access
    All menopausal hormone therapy is not alike
    Henry H. Lindner, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 721-722; DOI: https://doi.org/10.3949/ccjm.92c.12002
  • You have access
    Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both
    CME article
    Michelle D. Lundholm, MD and Keren Zhou, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 757-763; DOI: https://doi.org/10.3949/ccjm.92a.25069

    Latent autoimmune diabetes in adults shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy.

  • You have access
    In reply: All menopausal hormone therapy is not alike
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722; DOI: https://doi.org/10.3949/ccjm.92c.12003
  • You have access
    Should we continue guideline-directed medical therapy in patients with heart failure with improved ejection fraction?
    Nicole Ann Tesoro, MD and Sumanth Kumar Bandaru, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 667-670; DOI: https://doi.org/10.3949/ccjm.92a.24111

    Therapy should be continued even if left ventricular ejection fraction improves, as normalization or improvement does not guarantee a permanent recovery.

  • You have access
    Multiple scabietic nodules on the scrotum in a patient living with HIV infection
    Hidenori Nakagawa, MD, Akiko Imanishi, MD, Tomohiro Asaoka, MD and Michinori Shirano, MD, PhD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 654-655; DOI: https://doi.org/10.3949/ccjm.92a.24121

    A 21-year-old man presented with pruritic erythematous papules and nodules on the scrotum and linear keratotic burrows on the right wrist.

  • You have access
    Managing noninsulin glucose-lowering medications before surgery
    Adam Kaplan, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 651; DOI: https://doi.org/10.3949/ccjm.92c.11001
  • You have access
    Lipoprotein ‘little a’: More than a little target in the management of cardiovascular risk?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 647-648; DOI: https://doi.org/10.3949/ccjm.92b.11025

    Lipoprotein(a) was once believed to play no contributory role in the development of cardiovascular disease. That storyline has since flipped.

  • You have access
    Rethinking recovery in heart failure: Beyond improvement in left ventricular ejection fraction
    Nandan Kodur, BS and W. H. Wilson Tang, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 673-675; DOI: https://doi.org/10.3949/ccjm.92a.25078

    The authors discuss 3 unresolved questions about de-escalating and escalating guideline-directed medical therapy in patients with improved ejection fraction.

  • You have access
    Teprotumumab for thyroid eye disease: A reality check
    Julian Perry, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 702-703; DOI: https://doi.org/10.3949/ccjm.92a.25066

    Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.

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