Latest Articles

  • Statins may increase diabetes, but benefit still outweighs risk
    Byron J. Hoogwerf, MD, FACP, FACE
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 53-62; DOI: https://doi.org/10.3949/ccjm.90a.22069

    The weight of the evidence suggests that statin use is associated with an increased risk of new-onset diabetes mellitus, but the magnitude of the effect has varied across studies.

  • Which patients hospitalized with alcohol withdrawal syndrome should receive high-dose parenteral thiamine?
    Rahul B. Ganatra, MD, MPH, Anthony C. Breu, MD and Matthew V. Ronan, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 22-25; DOI: https://doi.org/10.3949/ccjm.90a.22026

    The authors briefly outline risk factors for Wernicke encephalopathy and when high-dose parenteral thiamine is indicated.

  • Making best use of bone turnover markers to monitor oral bisphosphonate therapy
    Sarah Keller, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 32-34; DOI: https://doi.org/10.3949/ccjm.90a.22092

    Clinical applications of bone turnover markers can include determining when to start or end a bisphosphonate “holiday” and measuring treatment response.

  • Median rhomboid glossitis caused by tongue-brushing
    Tatsuya Shindo, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 15-16; DOI: https://doi.org/10.3949/ccjm.90a.21111

    The patient had started vigorous brushing 1 month earlier after being told that she had bad breath.

  • What are my obligations to my incarcerated patient?
    Farah Acher Kaiksow, MD, MPP, Deval Patel, MD and Norman Fost, MD, MPH
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 18-21; DOI: https://doi.org/10.3949/ccjm.90a.22003

    A court order authorizes a blood transfusion, but the incarcerated patient refuses the transfusion. As the caregiver, am I obligated to follow the court order against the patient’s wishes?

  • Central vision loss in a 44-year-old woman
    Walker M. Schmidt, BS, Nirosha D. Perera, MD, Blake H. Fortes, MD, Benjamin A. Nelson, MD, Wendy M. Smith, MD and Hannah C. Nordhues, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 35-41; DOI: https://doi.org/10.3949/ccjm.90a.22038

    The patient had a wide range of symptoms and comorbidities, resulting in a complicated differential diagnosis. Careful evaluation eventually led to a focus on sexually transmitted infection.

  • Laboratory stewardship should be a priority in every hospital
    Anita J. Reddy, MD, MBA and Walter H. Henricks, MD
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 691-692; DOI: https://doi.org/10.3949/ccjm.89a.22068

    Considerations include indirect costs, downstream testing or other workup based on minor abnormalities uncovered during daily testing, and shortages in staff and supplies.

  • Is your patient at risk for NAFLD?
    Patress Ann Persons, MD, FACP, Sophie Bersoux, MD, MPH, FACP and Mary Helen Whited, MD, FACP
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 719-727; DOI: https://doi.org/10.3949/ccjm.89a.22005

    The authors review identifying individuals at risk, treatment options founded on lifestyle modification, and when to consider referring patients to a hepatologist.

  • Test ordering: Balancing the good for the many with the good for the one
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 672-673; DOI: https://doi.org/10.3949/ccjm.89b.12022

    Three articles this month address how we order clinical tests, one on the question of treating the patient with asymptomatic bacteriuria, the others on the advantages and disadvantages of standing orders for “daily labs” for inpatients.

  • Asymptomatic granules on the buccal mucosa
    Keiichi Ohta, DDS and Hitoshi Yoshimura, DDS, PhD
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 676-677; DOI: https://doi.org/10.3949/ccjm.89a.22025

    A healthy 35-year-old man presented with multiple small, white-yellow papules.

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