Latest Articles
- Reducing the risk of breast cancer
Breast cancer remains the most common malignancy in US women. Reducing this burden involves identification of high-risk individuals and personalized risk management.
- Spontaneous oral hematoma diagnosed as angina bullosa hemorrhagica
The lesions occur on the soft palate, buccal mucosa, and tongue, and only rarely on the masticatory mucosa such as the gingiva and hard palate.
- When should antithrombotic therapy be resumed after gastrointestinal bleeding?
The timing should be individualized after considering factors related to the bleeding event, thromboembolic risk, and patient comorbidities.
- Geriatric update 2022: Preventing Alzheimer disease and more
Key topics include Alzheimer dementia, effects of frailty and social isolation, COVID-19 risks in patients with dementia, hospital-at-home programs, deprescribing antihypertensive drugs, bisphosphonate-related fractures, and cannabis use.
- Scaly plaques in a malnourished patient
A markedly low serum zinc level and the characteristic location of the rash in a patient with long-standing alcohol use disorder and cirrhosis led to the correct diagnosis.
- Decongesting heart failure with diuretics: Easier to prescribe than to fully understand
Digging deep into the pathophysiology of diuretic resistance reveals complex interacting pathways. But none of these pathways can fully explain or be used to safely reverse diuretic resistance.
- How do I interpret and use quantitative buprenorphine and norbuprenorphine urine levels?
Confirmatory testing of urine samples can be useful in outpatient settings where buprenorphine dosing is not directly observed. But retaining and engaging the patient in effective treatment should be the ultimate goals of testing.
- How do we maximize diuresis in acute decompensated heart failure?
The initial goal is to maximize loop diuretic therapy using urine output or urinary sodium for guidance. Combination therapy can be used when patients respond poorly to escalating loop diuretic doses.
- Blue sclera: An overlooked finding of iron deficiency
The pathogenesis is thought to involve thinning of collagen fibers of the sclera due to iron deficiency, allowing the bluish color of the underlying uvea to become visible.
- Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance
New guidance on ordering, processing, and reporting urine cultures focuses on reducing unnecessary antibiotic use and the misdiagnosis of urinary tract infection.