Latest Articles

  • My adult patient’s hypercholesterolemia is not responding to statins—what’s next?

    Faaiq N. Aslam, MD, Mohamed G. Ibrahim, DO and Razvan Chirila, MD
    • Cleveland Clinic Journal of Medicine June 2025, 92 (6) 347-351;
    • DOI: https://doi.org/10.3949/ccjm.92a.24117

    • Further investigation is needed when patients do not meet their target low-density lipoprotein cholesterol levels with statin therapy alone.

  • Nitrogen: The unsung hero of vascular physiology

    Adam J. Brown, MD
    • Cleveland Clinic Journal of Medicine June 2025, 92 (6) 344-346;
    • DOI: https://doi.org/10.3949/ccjm.92a.24120

    • The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.

  • Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?

    Tark Abou-Elmagd, MD, MSc, MBBCh and Shraddha Narechania, MD
    • Cleveland Clinic Journal of Medicine June 2025, 92 (6) 339-343;
    • DOI: https://doi.org/10.3949/ccjm.92a.24083

    • The decision hinges on the subtype of pulmonary hypertension the patient has.

  • In defense of the anion gap

    Michael Emmett, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 269;
    • DOI: https://doi.org/10.3949/ccjm.92c.05001

  • New atrial fibrillation guideline: Modify risk, control rhythm, prevent progression

    Laura A. Campbell, MD, Jessica P. Ammon, DO, Rachana Kombathula, MD, Naa’irah Muhammad, MD and Christopher D. Jackson, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 291-296;
    • DOI: https://doi.org/10.3949/ccjm.92a.24067

    • Key updates in the new American guideline include recommendations for aggressive lifestyle and risk-factor modifications, annual assessment of thromboembolic risk, and early rhythm control.

  • In Reply: In defense of the anion gap

    Paloma Rodriguez Alvarez, MD, Vicente T. San Martin, MD and Oscar L. Morey-Vargas, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 269-270;
    • DOI: https://doi.org/10.3949/ccjm.92c.05002

  • The beat goes on: Highlights from the new American and European A-fib guidelines

    Sandra Howell, MBBS, MEd, MSc, MPhil, Alphonsus Liew, MBBS and Christopher Aldo Rinaldi, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 297-300;
    • DOI: https://doi.org/10.3949/ccjm.92a.25030

    • The authors discuss and compare the latest atrial fibrillation guidelines from American and European medical societies.

  • Tinea incognito

    Soniya Shony, MBBS, Carol Lobo, MBBS, MD and Sowmya Kaimal, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 271-272;
    • DOI: https://doi.org/10.3949/ccjm.92a.24099

    • This atypical form of dermatophyte infection is caused by local immune suppression from systemic or topical corticosteroids.

  • What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?

    Karthik Meiyappan Udayappan, MD and Christopher V. Anstine, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276;
    • DOI: https://doi.org/10.3949/ccjm.92a.24052

    • Computed tomography of the patient’s chest is indicated based on the robust association between clubbing and intrathoracic malignancy.

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    Managing right ventricular failure in the setting of pulmonary embolism

    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 301-309;
    • DOI: https://doi.org/10.3949/ccjm.92a.24069

    • The authors review current management strategies, including medical, percutaneous interventional, and surgical options, and discuss recent advances in the field.

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