Latest Articles

  • Do I need to treat supine hypertension in my hospitalized patient?

    Katherine Sherman, MD and Robert Lichtenberg, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 285-289;
    • DOI: https://doi.org/10.3949/ccjm.92a.24092

    • Inpatients with an elevated supine blood pressure should be evaluated for orthostatic changes before treatment is considered.

  • Alpha-gal syndrome: Recognizing and managing a tick-bite–related meat allergy

    Zehra Naseem, MD, Aun Muhammad, MD, Arjun Chatterjee, MD and Alberto Rubio-Tapia, MD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 311-319;
    • DOI: https://doi.org/10.3949/ccjm.92a.24072

    • Alpha-gal syndrome is an emerging allergic condition in which immunoglobulin E–mediated symptoms are triggered a few hours after an affected person consumes mammalian meat.

  • Does my adult patient need a measles vaccine?

    Kaitlyn R. Rivard, PharmD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 279-282;
    • DOI: https://doi.org/10.3949/ccjm.92a.25038

    • Possibly. Adults without acceptable presumptive evidence of immunity to measles should receive 1 dose of the measles-mumps-rubella vaccine, and 2 doses are recommended for adults in special situations.

  • The gift of lasting immunity

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine May 2025, 92 (5) 263-264;
    • DOI: https://doi.org/10.3949/ccjm.92b.05025

    • Measles vaccine–induced immunity, although not necessarily lifelong for all individuals, is quite durable.

  • Psychedelics in the medical toolbox?

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 200-201;
    • DOI: https://doi.org/10.3949/ccjm.92b.04025

    • Given the historical association of psychedelics as “recreational” mind-altering compounds within countercultures of the 1960s and 1970s, their current introduction into several aspects of medical practice is a surprise to many.

  • Prolonged venous filling time and dependent rubor in a patient with peripheral artery disease

    Scott L. Hagan, MD and Jeffrey W. Redinger, MD
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 205-206;
    • DOI: https://doi.org/10.3949/ccjm.92a.24056

    • Physical examination in a man who presented with foot pain revealed absent bilateral posterior tibial and dorsalis pedis pulses and dusky erythema of both feet.

  • Subclinical hypothyroidism: What’s in a name?

    Jennifer S. Mammen, MD, PhD
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 233-235;
    • DOI: https://doi.org/10.3949/ccjm.92a.25028

    • Clinicians should remain thoughtful about the variability in aging biology and not be blinded by a name.

  • Psychedelics, spirituality, and existential distress in patients at the end of life

    Nicole Cornish, PharmD, Tara Coles, MD, M. Jennifer Cheng, MD, Claudia Ruiz Sotomayor, MD, DBe, Aaron Wolfgang, MD and Christopher Spevak, MD, MPH, JD
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 248-254;
    • DOI: https://doi.org/10.3949/ccjm.92a.24100

    • The authors explore the role of psychedelics in addressing patients’ spiritual and existential suffering at the end of life from a medical, ethical, and legal perspective.

  • Should glucagon-like peptide 1 receptor agonists be withheld during the preoperative period?

    Sneha Mishra, MBBS, Patress A. Persons, MD and Sophie Bersoux, MD, MPH
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 209-211;
    • DOI: https://doi.org/10.3949/ccjm.92a.24110

    • Clinical judgment should guide this decision, taking into account patient symptoms and the presence of factors that may delay gastric emptying and increase risk for aspiration.

  • 2024 ACC/AHA guideline on perioperative cardiovascular management before noncardiac surgery: What’s new?

    Steven L. Cohn, MD
    • Cleveland Clinic Journal of Medicine April 2025, 92 (4) 213-219;
    • DOI: https://doi.org/10.3949/ccjm.92a.24125

    • The author highlights key changes and recommendations of the new guideline, how they differ from previous and other society guidelines, and ongoing challenges and unresolved issues in perioperative care.

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