Latest Articles
- Nearly a century of using glucocorticoids in patients with active infection
Why would we consider dampening the immune response with glucocorticoids when a patient has an active infection?
- MDA5 dermatomyositis: Unveiling a potentially life-threatening disease
Timely diagnosis and initiation of aggressive immunosuppressive therapy are key to improving the 40% overall mortality rate in patients with MDA5 dermatomyositis.
- Hold ACE inhibitors and ARBs before noncardiac surgery? Emerging evidence suggests a patient-specific approach
Judicious withholding of ACE inhibitors and ARBs in vulnerable populations—and promptly resuming them—may strike the safest balance between renal protection and hemodynamic stability.
- Do patients with severe community-acquired bacterial pneumonia benefit from systemic corticosteroids?
Recent evidence has swung the pendulum back in favor of using corticosteroids in patients with severe community-acquired pneumonia.
- Flexibility is warranted in applying prescribing guidelines
Discontinuation of benzodiazepines in chronic users may be associated with a small increase in mortality and a higher risk of adverse events, especially in the short term after cessation.
- An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel
Oral norgestrel, the first daily oral contraceptive pill available over the counter in the United States, is a safe, effective addition to existing over-the-counter contraceptive options.
- How can I help my pregnant patients quit using tobacco?
Clinicians should screen for tobacco use and follow-up with pregnancy-specific messaging during each visit, building on any motivation the patient has to quit.
- What is the role of cystatin C in estimating glomerular filtration rate and guiding medication dosing?
A dual-marker strategy using both serum creatinine and cystatin C is recommended for certain patients in whom serum creatinine alone may not accurately reflect kidney function.
- Optimizing hypertension treatment: Evidence-based approaches and new drugs
The authors discuss current evidence-based approaches to managing hypertension and optimizing blood pressure control through a series of cases representing common clinical scenarios.