Latest Articles

  • Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?
    CME article
    Dylan T. Timberlake, MD, Sushmitha Boppana, MD and James Fernandez, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 47-53; DOI: https://doi.org/10.3949/ccjm.93a.25026
  • Pseudoxanthoma elasticum
    Kathleen Kramer, MD, Sama Alazawi, DO and Rudy Schmiedecke, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 13-14; DOI: https://doi.org/10.3949/ccjm.93a.25021

    The patient presented for evaluation of yellowish plaques on her neck that had been present since childhood.

  • More on the myths and perceived magic of corticosteroids
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 6-7; DOI: https://doi.org/10.3949/ccjm.93b.01026

    It is widely accepted that corticosteroids can partially prevent infusion reactions to intravenous diagnostic and therapeutic agents, but evidence to support this concept is scant.

  • Update on antiobesity pharmacotherapy in adults: Current and emerging options
    Farah Ziyadeh, MD, Sara Saliba, MD, RD, Dania Salih Bacha, MD, Yael Mauer, MD, MPH, Marcio L. Griebeler, MD, DABOM and Bartolome Burguera, MD, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 36-46; DOI: https://doi.org/10.3949/ccjm.93a.24112

    The authors review antiobesity medications that are currently available or under investigation and discuss how to personalize obesity treatment.

  • A young woman with Kallmann syndrome and acute neurologic symptoms
    A young woman with Kallmann syndrome and acute neurologic symptoms
    Jumaina F. Ali, MBChB, Adhithya Sankar, MBChB, PhD, Mohammed S. O. Ahmed, MBBS, MSc, Mark Woodward, BSc (Hons), MBChB and Akheel A. Syed, MBBS, PhD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 29-34; DOI: https://doi.org/10.3949/ccjm.93a.25010
  • Vaccine hesitancy: Where are we heading?
    Sherif Beniameen Mossad, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 21-26; DOI: https://doi.org/10.3949/ccjm.93a.25104

    Vaccination recently was hailed as one of the top 10 public health achievements of the 20th century; now, the World Health Organization lists vaccine hesitancy among the top 10 threats to global health.

  • Multicentric reticulohistiocytosis
    Atul Khasnis, MD, MS and Joseph M. Dyer, DO
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 9-11; DOI: https://doi.org/10.3949/ccjm.93a.24124

    A 58-year-old man presented with a 2-month history of joint pain and swelling and a rash.

  • Atrial fibrillation in patients with obesity: How can we optimize management?
    Asim Kichloo, MD, Ivan Magallanes Marrufo, MPH and Suhaib Andrabi, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 17-20; DOI: https://doi.org/10.3949/ccjm.93a.25032

    Heart rate and rhythm control therapies often must be adjusted when treating patients with obesity, while other measures can reduce the onset or recurrence of atrial fibrillation.

  • In reply: All menopausal hormone therapy is not alike
    Samantha F. Butts, MD, MSCE
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 722; DOI: https://doi.org/10.3949/ccjm.92c.12003
  • Skin manifestations of mpox
    James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737; DOI: https://doi.org/10.3949/ccjm.92a.25022

    The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

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