Latest Articles

  • Amoxicillin rash in infectious mononucleosis
    Yasuhiro Kano, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 335-337; DOI: https://doi.org/10.3949/ccjm.92a.24039

    A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.

  • High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management
    Maximilian C. Volk, DO, Bianca Honnekeri, MD, Joanna Ghobrial, MD, Mazen Hanna, MD, Sanjeeb Bhattacharya, MD, Lee Kirksey, MD, J. Emanuel Finet, MD and Heba Wassif, MD, MPH
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 362-371; DOI: https://doi.org/10.3949/ccjm.92a.24114

    Arteriovenous high-output heart failure is likely underdiagnosed because many clinicians are uncertain about when and how to evaluate for it.

  • Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice
    CME article
    Syed Bukhari, MD, MHA, Mohamed Ghoweba, MD, Syed Zamrak Khan, MD, Ammar Saati, MD and Marcelo Gomes, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 353-361; DOI: https://doi.org/10.3949/ccjm.92a.24061

    Preapproval trials of direct oral anticoagulants excluded patients with extreme body weight and advanced kidney and liver disease and those who had undergone bariatric surgery. Cautious decision-making in these patients is warranted.

  • My adult patient’s hypercholesterolemia is not responding to statins—what’s next?
    Faaiq N. Aslam, MD, Mohamed G. Ibrahim, DO and Razvan Chirila, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 347-351; DOI: https://doi.org/10.3949/ccjm.92a.24117

    Further investigation is needed when patients do not meet their target low-density lipoprotein cholesterol levels with statin therapy alone.

  • The gift of lasting immunity
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 263-264; DOI: https://doi.org/10.3949/ccjm.92b.05025

    Measles vaccine–induced immunity, although not necessarily lifelong for all individuals, is quite durable.

  • Alpha-gal syndrome: Recognizing and managing a tick-bite–related meat allergy
    Zehra Naseem, MD, Aun Muhammad, MD, Arjun Chatterjee, MD and Alberto Rubio-Tapia, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 311-319; DOI: https://doi.org/10.3949/ccjm.92a.24072

    Alpha-gal syndrome is an emerging allergic condition in which immunoglobulin E–mediated symptoms are triggered a few hours after an affected person consumes mammalian meat.

  • Managing right ventricular failure in the setting of pulmonary embolism
    Managing right ventricular failure in the setting of pulmonary embolism
    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 301-309; DOI: https://doi.org/10.3949/ccjm.92a.24069

    The authors review current management strategies, including medical, percutaneous interventional, and surgical options, and discuss recent advances in the field.

  • The beat goes on: Highlights from the new American and European A-fib guidelines
    Sandra Howell, MBBS, MEd, MSc, MPhil, Alphonsus Liew, MBBS and Christopher Aldo Rinaldi, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 297-300; DOI: https://doi.org/10.3949/ccjm.92a.25030

    The authors discuss and compare the latest atrial fibrillation guidelines from American and European medical societies.

  • What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
    Karthik Meiyappan Udayappan, MD and Christopher V. Anstine, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276; DOI: https://doi.org/10.3949/ccjm.92a.24052

    Computed tomography of the patient’s chest is indicated based on the robust association between clubbing and intrathoracic malignancy.

  • Tinea incognito
    Soniya Shony, MBBS, Carol Lobo, MBBS, MD and Sowmya Kaimal, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 271-272; DOI: https://doi.org/10.3949/ccjm.92a.24099

    This atypical form of dermatophyte infection is caused by local immune suppression from systemic or topical corticosteroids.

Pages