Latest Articles
- Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce
Early trials suggested a link between GLP-1 receptor agonists and pancreatitis, but recent large meta-analyses do not support a class-wide risk.
- Newer diabetes drugs: Surprising shared benefits and unique side effects
The shared beneficial effects of the SGLT2 inhibitors and the GLP-1 receptor agonists, drugs with distinct mechanisms of action, may have an anti-inflammatory explanation.
- Refractory granuloma annulare
A 77-year-old woman presented with a rash characterized by orange-yellow papules coalescing into erythematous annular plaques on her hands, trunk, and legs.
- Managing the side effects of sodium-glucose cotransporter-2 inhibitors
The authors review recent evidence on the side effects of sodium-glucose cotransporter-2 inhibitors and corresponding strategies for preventing and managing them.
- The overlooked and undertreated perils of premature ovarian insufficiency
Physicians should be alert to the possibility of undiagnosed premature ovarian insufficiency—loss of ovarian function before age 40—and know what to do if the condition is suspected.
- Breast cancer risk and screening for transgender and gender-diverse individuals
Evidence on breast cancer risk in transgender and gender-diverse individuals is limited, and recent guidelines are primarily based on expert consensus, retrospective cohort studies, and extrapolation from cisgender populations.
- Insights from the LAAOS III trial of left atrial appendage occlusion to prevent stroke in atrial fibrillation
Left atrial appendage occlusion added to routine cardiac surgery reduced the risk of ischemic stroke or systemic embolism in patients with atrial fibrillation and high stroke risk, but questions remain.
- How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?
Diarrhea and colitis, which can result from infection or be complications of immune checkpoint inhibitors, require prompt evaluation so that appropriate treatment can be started.
Fecal microbiota transplantation: Current evidence and future directionsFecal microbiota transplantation is recognized for effectively treating recurrent Clostridioides difficile infection, prompting further investigation into its other possible clinical applications.
- Recreational cannabis legalization: Potential implications for individual and community health
The authors discuss evidence on the effects of legalized recreational cannabis on overall cannabis consumption, crime, traffic safety, and individual and community health.
