Latest Articles
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
- Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?
The decision hinges on the subtype of pulmonary hypertension the patient has.
- Amoxicillin rash in infectious mononucleosis
A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.
- Tinea incognito
This atypical form of dermatophyte infection is caused by local immune suppression from systemic or topical corticosteroids.
- New atrial fibrillation guideline: Modify risk, control rhythm, prevent progression
Key updates in the new American guideline include recommendations for aggressive lifestyle and risk-factor modifications, annual assessment of thromboembolic risk, and early rhythm control.
- Does my adult patient need a measles vaccine?
Possibly. Adults without acceptable presumptive evidence of immunity to measles should receive 1 dose of the measles-mumps-rubella vaccine, and 2 doses are recommended for adults in special situations.
- Do I need to treat supine hypertension in my hospitalized patient?
Inpatients with an elevated supine blood pressure should be evaluated for orthostatic changes before treatment is considered.

