Latest Articles

  • Managing chronic kidney disease according to KDIGO risk categories: A primer for primary care
    Managing chronic kidney disease according to KDIGO risk categories: A primer for primary care
    Rodolfo J. Galindo, MD, Diana Soliman, MD, Joshua J. Neumiller, PharmD, Jay H. Shubrook, DO and Katherine R. Tuttle, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 353-365; DOI: https://doi.org/10.3949/ccjm.93a.25072

    The authors review the KDIGO guideline updates and provide a simplified treatment algorithm for non-nephrologists, focusing on medication sequencing and monitoring.

  • Hematochezia in a patient with end-stage renal disease
    Brennan Gioe, MD, Conrad Fernandes, MD, E. Celia Marginean, MD and Stalin Subramanian, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 333-338; DOI: https://doi.org/10.3949/ccjm.93a.25097

    The patient developed gastrointestinal bleeding after being started on intravenous heparin following thrombectomy and angioplasty for acute limb ischemia.

  • Letter: Diagnostic challenges in severe autoimmune hemolysis
    Sadeem Muhammad Rizwan, MBBS
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 317; DOI: https://doi.org/10.3949/ccjm.93c.06001
  • In Reply: Diagnostic challenges in severe autoimmune hemolysis
    Sindu Iska, MD, María Herrán, MD, You Li, MD, Maria Teresa Bejarano, MD, Chakra P. Chaulagain, MD and Chieh-Lin Fu, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 317-318; DOI: https://doi.org/10.3949/ccjm.93c.06002
  • Pseudocellulitis, a vague term for a specific diagnostic challenge
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 313-314; DOI: https://doi.org/10.3949/ccjm.93b.06026

    There are infectious, vascular, and inflammatory conditions that can mimic cellulitis sufficiently to prompt admission and initial treatment with intravenous antibiotics.

  • Hyperactive delirium in hospitalized older adults: Balancing medication choices and QTc prolongation risk
    Emily Hao, MD, Tamara Lhungay, MD, Jessica Arabi, PharmD, BCCCP, Colin J. Harrington, MD and Iva Neupane, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 325-330; DOI: https://doi.org/10.3949/ccjm.93a.25092

    Medications for managing delirium symptoms, particularly antipsychotics, are associated with prolongation of the QT interval, which is a risk factor for the development of fatal arrhythmias.

  • Disseminated coccidioidomycosis masquerading as bacterial cellulitis
    Santana Maria Bachaalany, DO, Nelson Nicolasora, MD, Lindsay Ackerman, MD, Ghassan Ibrahim, MD and Trent Smith, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 321-323; DOI: https://doi.org/10.3949/ccjm.93a.25096

    The patient exhibited signs of sepsis along with progressive left breast erythema, induration, and pain.

  • In Reply: Type 2 diabetes prevention after acute pancreatitis
    Magnus Chun, MD, Amrit Narwan, MD, Ryan Parto, MD, Andrew John Cruz, MD, Jiayi Ge, MD, Zan Ferrin, DO, Namrita George, DO, Evelyn Kue, DO, Adam Khattak, DO, Vignan Manne, MD and Amber Champion, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 319; DOI: https://doi.org/10.3949/ccjm.93c.06004
  • KDIGO chronic kidney disease heat map: Let the colors be your guide!
    Crystal Gadegbeku, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 366-367; DOI: https://doi.org/10.3949/ccjm.93a.26017

    Clinicians need to adopt early interventions that can alter the course of chronic kidney disease for patients.

  • Potassium-competitive acid blockers: Clinical pearls and practical insights
    Hisham Wehbe, MD and Claire Beveridge, MD
    Cleveland Clinic Journal of Medicine June 2026, 93 (6) 341-346; DOI: https://doi.org/10.3949/ccjm.93a.25070

    P-CABs provide rapid, potent, predictable acid suppression without the need for timing around meals, but their current role is focused and limited.

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