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Cleveland Clinic Journal of Medicine

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Latest Articles

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    Odontogenic cutaneous fistula
    Sagar Khanna, BDS, DDS
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 399-400; DOI: https://doi.org/10.3949/ccjm.92a.24096

    A 55-year-old woman with a history of systemic lupus erythematosus and secondary Sjögren syndrome presented with a 2-year history of facial swelling and intermittent drainage from a skin lesion on her left jaw.

  • You have access
    Immunotherapy meets William Shakespeare
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 390-391; DOI: https://doi.org/10.3949/ccjm.92b.07025

    Immune checkpoint inhibitors are potentially life-saving therapies that can trigger a wide range of autoimmune pathology.

  • You have access
    In Reply: Managing right ventricular failure in the setting of pulmonary embolism
    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 396-397; DOI: https://doi.org/10.3949/ccjm.92c.07004
  • You have access
    Most elderly patients with subclinical hypothyroidism do not need to be treated
    Scott Selinger, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 395; DOI: https://doi.org/10.3949/ccjm.92c.07001
  • You have access
    In Reply: Most elderly patients with subclinical hypothyroidism do not need to be treated
    Risheng Xu, DO, Nicola Abate, MD, Nalini Ram, MD and Kristina Little, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 395; DOI: https://doi.org/10.3949/ccjm.92c.07002
  • You have access
    Amoxicillin rash in infectious mononucleosis
    Yasuhiro Kano, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 335-337; DOI: https://doi.org/10.3949/ccjm.92a.24039

    A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.

  • You have access
    High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management
    Maximilian C. Volk, DO, Bianca Honnekeri, MD, Joanna Ghobrial, MD, Mazen Hanna, MD, Sanjeeb Bhattacharya, MD, Lee Kirksey, MD, J. Emanuel Finet, MD and Heba Wassif, MD, MPH
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 362-371; DOI: https://doi.org/10.3949/ccjm.92a.24114

    Arteriovenous high-output heart failure is likely underdiagnosed because many clinicians are uncertain about when and how to evaluate for it.

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    Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice
    CME article
    Syed Bukhari, MD, MHA, Mohamed Ghoweba, MD, Syed Zamrak Khan, MD, Ammar Saati, MD and Marcelo Gomes, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 353-361; DOI: https://doi.org/10.3949/ccjm.92a.24061

    Preapproval trials of direct oral anticoagulants excluded patients with extreme body weight and advanced kidney and liver disease and those who had undergone bariatric surgery. Cautious decision-making in these patients is warranted.

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    My adult patient’s hypercholesterolemia is not responding to statins—what’s next?
    Faaiq N. Aslam, MD, Mohamed G. Ibrahim, DO and Razvan Chirila, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 347-351; DOI: https://doi.org/10.3949/ccjm.92a.24117

    Further investigation is needed when patients do not meet their target low-density lipoprotein cholesterol levels with statin therapy alone.

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    Nitrogen: The unsung hero of vascular physiology
    Adam J. Brown, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 344-346; DOI: https://doi.org/10.3949/ccjm.92a.24120

    The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.

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