Latest Articles

  • Why 25-dehydroxyvitamin D is a negative acute-phase reactant
    Maria J. Antonelli, MD, Irving Kushner, MD and Murray Epstein, MD, FASN, FACP
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 535; DOI: https://doi.org/10.3949/ccjm.90c.09001
  • Should I consider metformin therapy for weight loss in patients with obesity but without diabetes?
    Paloma Rodriguez, MD, Kevin M. Pantalone, DO, ECNU, FACE, Marcio L. Griebeler, MD and Bartolome Burguera, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 545-548; DOI: https://doi.org/10.3949/ccjm.90a.22096
  • Petaloid dermatosis affecting the scalp and genitalia
    Taylor A. Bullock, MD, Shruti Agrawal, MD and Wilma Bergfeld, MD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 527-528; DOI: https://doi.org/10.3949/ccjm.90a.22100
  • If a patient has cirrhosis, should I correct coagulation abnormalities before a minor invasive procedure?
    Emily B. Wolf, MD, Marie Plante, MD and Razvan M. Chirila, MD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 541-543; DOI: https://doi.org/10.3949/ccjm.90a.23005

    Hemostatic abnormalities in cirrhosis can include thrombocytopenia, prolonged prothrombin time, prolonged activated partial thromboplastin time, elevated international normalized ratio, and decreased fibrinogen.

  • A practical guide for buprenorphine initiation in the primary care setting
    Roberto León-Barriera, MD, Samantha Jayne Zwiebel, MD, MA and Vania Modesto-Lowe, MD, MPH
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 557-564; DOI: https://doi.org/10.3949/ccjm.90a.23022

    The authors review changes in prescribing laws and outline buprenorphine induction protocols that can be adopted in the primary care setting.

  • Mpox: Keep it on the differential
    Sara L. Clemens, MD and Stuart N. Isaacs, MD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 565-575; DOI: https://doi.org/10.3949/ccjm.90a.23020
  • Persistent rectal pain leading to diffuse pustules
    Lydia Cassard, BA, Taylor A. Bullock, MD, Wyatt Andrasik, MD and Anthony P. Fernandez, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 537-539; DOI: https://doi.org/10.3949/ccjm.90a.22089

    The authors relate the workup of a 34-year-old patient with a history of syphilis and human immunodeficiency virus.

  • Born again: The many lives of metformin
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 523-524; DOI: https://doi.org/10.3949/ccjm.90b.09023

    Repurposing old drugs for new indications is not a new drug-development strategy.

  • In Reply: Computed tomography of the head
    Gilad Muth, DO, Thomas A. Bayer, MD and Richard Libman, MD
    Cleveland Clinic Journal of Medicine August 2023, 90 (8) 461; DOI: https://doi.org/10.3949/ccjm.90c.08002
  • To prophylax or not to prophylax for endocarditis: Still a question
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2023, 90 (8) 455-456; DOI: https://doi.org/10.3949/ccjm.90b.08023

    Give prophylactic antibiotics before invasive dental procedures? On the surface, it may seem sensible. But we have more to learn about the successful clearance of bacteria from the bloodstream and why protective mechanisms occasionally fail.

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