Hepatology

  • What is the role for terlipressin in hepatorenal syndrome?

    Stephanie N. Bass, PharmD, Aanchal Kapoor, MD and Christina C. Lindenmeyer, MD
    • Cleveland Clinic Journal of Medicine November 2023, 90 (11) 664-667;
    • DOI: https://doi.org/10.3949/ccjm.90a.23037

    • The drug is recommended as a first-line treatment of hepatorenal syndrome-related acute kidney injury, but it is associated with respiratory failure, especially in the setting of albumin administration, and certain comorbidities may increase the risk.

  • Elevated aminotransferases in a 62-year-old woman

    Gregory W. Rutecki, MD, Shahana Prakash, MD, Steven Moore, MD, PhD, Anthony Snow, MD and Kyle E. Brown, MD, FAASLD
    • Cleveland Clinic Journal of Medicine November 2023, 90 (11) 669-674;
    • DOI: https://doi.org/10.3949/ccjm.90a.23011

    • Her medical history included gastroesophageal reflux disease and Sjögren syndrome. She had recently returned from travel to Malaysia.

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    Cirrhosis: Primary care approaches to screening, immunization, and lifestyle modifications

    Asim Kichloo, MD, Michael Aljadah, MD, Michael Albosta, MD, Zain El-Amir, MD, Ghazaleh Goldar, MD, Muhammed Zatmar Khan, MD, Dushyant Singh Dahiya, MD and Farah Wani, MD
    • Cleveland Clinic Journal of Medicine November 2023, 90 (11) 693-701;
    • DOI: https://doi.org/10.3949/ccjm.90a.21043

    • The authors review management of cirrhosis and complications such as esophageal varices and hepatocellular carcinoma, as well as chemical and medication exposures.

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    Portopulmonary hypertension: A focused review for the internist

    Mamta S. Chhabria, MD, Leela Krishna Teja Boppana, MD, Gaurav Manek, MD and Adriano R. Tonelli, MD, MSc
    • Cleveland Clinic Journal of Medicine October 2023, 90 (10) 632-639;
    • DOI: https://doi.org/10.3949/ccjm.90a.23023

    • Key aspects of screening, diagnosis, and treatment, and a review of the various pulmonary hemodynamic patterns encountered in patients with liver disease.

  • If a patient has cirrhosis, should I correct coagulation abnormalities before a minor invasive procedure?

    Emily B. Wolf, MD, Marie Plante, MD and Razvan M. Chirila, MD
    • Cleveland Clinic Journal of Medicine September 2023, 90 (9) 541-543;
    • DOI: https://doi.org/10.3949/ccjm.90a.23005

    • Hemostatic abnormalities in cirrhosis can include thrombocytopenia, prolonged prothrombin time, prolonged activated partial thromboplastin time, elevated international normalized ratio, and decreased fibrinogen.

  • Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome

    Sarah Khan, MD and Maureen Linganna, MD
    • Cleveland Clinic Journal of Medicine April 2023, 90 (4) 209-213;
    • DOI: https://doi.org/10.3949/ccjm.90a.22028

    • A review of recommendations from the American Association for the Study of Liver Diseases.

  • Is your patient at risk for NAFLD?

    Patress Ann Persons, MD, FACP, Sophie Bersoux, MD, MPH, FACP and Mary Helen Whited, MD, FACP
    • Cleveland Clinic Journal of Medicine December 2022, 89 (12) 719-727;
    • DOI: https://doi.org/10.3949/ccjm.89a.22005

    • The authors review identifying individuals at risk, treatment options founded on lifestyle modification, and when to consider referring patients to a hepatologist.

  • Circulating lipids are not all bad: An LDL mimic that may be only skin deep

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine August 2022, 89 (8) 422-423;
    • DOI: https://doi.org/10.3949/ccjm.89b.08022

    • Although lipoprotein-X separates out by density in the low-density lipoprotein (LDL) fraction and thus may appear as LDL in the laboratory report, it is biologically unique.

  • Does incidentally detected common bile duct dilation need evaluation?

    Anam Rizvi, MD, Amrita Sethi, MD, John Poneros, MD and Kavel H. Visrodia, MD
    • Cleveland Clinic Journal of Medicine June 2022, 89 (6) 315-319;
    • DOI: https://doi.org/10.3949/ccjm.89a.21029

    • A patient-centered approach and knowledge of the diagnostic yield of further testing helps determine appropriate management.

  • Spider nevi secondary to alcoholic chronic liver disease

    Mohamed Adam Ali, MBBS, BSc, FHEA
    • Cleveland Clinic Journal of Medicine June 2022, 89 (6) 301-302;
    • DOI: https://doi.org/10.3949/ccjm.89a.21064

    • The lesions blanched when pressure was applied centrally and refilled from the center outward when pressure was released.

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